biofisika

Nonlinear material and ionic transport through membrane nanotubes

D. V Ivchenkov, P. I. Kuzmin, T. R. Galimzyanov, A. V Shnyrova, P. V Bashkirov, V. A. Frolov

Biochim. Biophys. Acta - Biomembr. 2021, 1863, DOI 10.1016/j.bbamem.2021.183677 (2021)

Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells

L. M. Nolan, A. K. Cain, T. Clamens, R. C. D. Furniss, E. Manoli, M. A. Sainz-Polo, G. Dougan, D. Albesa- Jové, J. Parkhill, D. A. I. Mavridou, D. A. I. Mavridou, A. Filloux

Nat. Microbiol. 2021, DOI 10.1038/s41564-021-00950-8. (2021)

Antibodies response induced by recombinant virus-like particles from Triatoma virus and chimeric antigens from Trypanosoma cruzi

A. M. V. Queiroz, Y. A. Yanshina, E. T. da Silva Rodrigues, F. L. N. Santos, P. A. F. Celedon, S. Maheshwari, S. B. Gabelli, C. S. P. Rubio, A. Durana, D. M. A. Guérin, M. S. Silva

Vaccine 2021, 39, 4723 (2021)

Super-Resolution Microscopy Using a Bioorthogonal-Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in Living Cells

M. Lorizate, O. Terrones, J. A. Nieto-Garai, I. Rojo-Bartolomé, D. Ciceri, O. Morana, J. Olazar-Intxausti, A. Arboleya, A. Martin, M. Szynkiewicz, J. B. de la Serna, F.-X. Contreras

Small Methods 2021, DOI 10.1002/smtd.202100430 (2021)

In Vitro Cellular Uptake Studies of Self-Assembled Fluorinated Nanoparticles Labelled with Antibodies

M. Atabakhshi-Kashi, M. Carril, H. Mahdavi, W. J. Parak, C. Carrillo-Carrion, K. Khajeh

Nanomaterials 2021, 11, DOI 10.3390/nano11081906 (2021)

Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison

J. Carrasco-Pujante, C. Bringas, I. Malaina, M. Fedetz, L. Martínez, G. Pérez-Yarza, M. D. Boyano, M. , Berdieva, A. Goodkov, J. I. López, S. Knafo, I. M. De la Fuente

Front. Microbiol. 2021, 12, DOI 10.3389/fmicb.2021.707086 (2021)

Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size

D. G. Bullón, K. B. Uribe, J. Amuategi, C. Martín, H. Ostolaza

FEBS J. 2021, DOI 10.1111/febs.16107 (2021)

Predicting Metabolic Reaction Networks with Perturbation-Theory Machine Learning (PTML) Models

K. Diéguez-Santana, G. M. Casañola-Martin, J. R. Green, B. Rasulev, H. González-Díaz

Curr. Top. Med. Chem. 2021, 21, 819 (2021)

The Role of Non-Covalent Interactions on Cluster Formation: Pentamer, Hexamers and Heptamer of Difluoromethane

C. Calabrese, B. Temelso, I. Usabiaga, N. A. Seifert, F. J. Basterretxea, G. Prampolini, G. C. Shields, B. H. Pate, L. Evangelisti, E. J. Cocinero

Angew. Chemie - Int. Ed. 2021, 60, 16894 (2021)

LDLR variants functional characterization: Contribution to variant classification

A. C. Alves, S. Azevedo, A. Benito-Vicente, R. Graça, U. Galicia-Garcia, P. Barros, P. Jordan, C. Martin, M. Bourbon

Atherosclerosis 2021, 329, 14 (2021)

Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts

M. Bortolomeazzi, M. R. Keddar, L. Montorsi, A. Acha-Sagredo, L. Benedetti, D. Temelkovski, S. Choi, N. Petrov, K. Todd, P. Wai, J. Spencer, F. D. Ciccarelli

Gastroenterology 2021, DOI 10.1053/j.gastro.2021.06.064. (2021)

Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers

E. Rujas, I. Kucharska, Y. Z. Tan, S. Benlekbir, H. Cui, T. Zhao, G. A. Wasney, P. Budylowski, F. Guvenc, J. C. Newton, B. Treanor, J.-P. Julien

Nat. Commun. 2021, 12, DOI 10.1038/s41467-021-23825-2 (2021)

Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain

D. J. López, J. A. Rodríguez, S. Bañuelos

Int. J. Mol. Sci. 2021, 22, DOI 10.3390/ijms22126308 (2021)

Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach

L. Dublang, J. Underhaug, M. I. Flydal, L. Velasco-Carneros, J.-D. Maréchal, F. Moro, M. D. Boyano, A. Martinez, A. Muga

Cancers (Basel). 2021, 13, DOI 10.3390/cancers13122936 (2021)

Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/tacrolimus formulations

A. Hidalgo, C. Garcia-Mouton, C. Autilio, P. Carravilla, G. Orellana, M. N. Islam, J. Bhattacharya, S. Bhattacharya, A. Cruz, J. Pérez-Gil

J. Control. Release 2021, 329, 205 (2021)

The emerging landscape of single-molecule protein sequencing technologies

J. A. Alfaro, P. Bohländer, M. Dai, M. Filius, C. J. Howard, X. F. van Kooten, S. Ohayon, A. Pomorski, S. Schmid, A. Aksimentiev, A. Meller, C. Joo

Nat. Methods 2021, 18, 604 (2021)

Oligonucleotide-Directed Protein Threading Through a Rigid Nanopore

G. Celaya, D. Rodriguez-Larrea

Oligonucleotide-Directed Protein Threading through a Rigid Nanopore, 2021. (2021)

SR-B1, a Key Receptor Involved in the Progression of Cardiovascular Disease: A Perspective from Mice and Human Genetic Studies

Gracia-Rubio Irene, Martín César, Civeira Fernando, Cenarro Ana

Biomedicines 2021, 9, DOI 10.3390/biomedicines9060612 (2021)

FORTIS: a live-cell assay to monitor AMPA receptors using pH-sensitive fluorescence tags

M. Calleja-Felipe, M. N. Wojtas, M. Diaz-González, D. Ciceri, R. Escribano, A. Ouro, M. Morales, S. Knafo

Transl. Psychiatry 2021, 11, DOI 10.1038/s41398-021-01457-w (2021)

An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel

J. Urrutia, A. Aguado, C. Gomis-Perez, A. Muguruza-Montero, O. R. Ballesteros, J. Zhang, E. Nuñez, C. Malo, H. J. Chung, A. Leonardo, A. Bergara, A. Villarroel

BMC Biol. 2021, 19, DOI 10.1186/s12915-021- 01040-1. (2021)

Degradation of Drug Delivery Nanocarriers and Payload Release: A Review of Physical Methods for Tracing Nanocarrier Biological Fate

P. M. Perrigue, R. A. Murray, A. Mielcarek, A. Henschke, S. E. Moya

Pharmaceutics 2021, 13, DOI 10.3390/pharmaceutics13060770 (2021)

CHO/LY-B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes

B. G. Monasterio, N. Jiménez-Rojo, A. B. García-Arribas, H. Riezman, F. M. Goñi, A. Alonso

FASEB J. 2021, 35, DOI 10.1096/fj.202001879RR. (2021)

Single-aminoacid discrimination in proteins with homogeneous nanopore sensors and neural networks

D. Rodriguez-Larrea

Biosens. Bioelectron. 2021, 180, DOI 10.1016/j.bios.2021.113108. (2021)

Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure

M. D. González, A. Buberman, M. Morales, I. Ferrer, S. Knafo

Front. Synaptic Neurosci. 2021, 13, DOI 10.3389/fnsyn.2021.683290 (2021)

Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells

Y. Vado, G. Puras, M. Rosique, C. Martin, J. L. Pedraz, S. Jebari-Benslaiman, M. M. de Pancorbo, J. Zarate, G. P. de Nanclares

Pharmaceutics 2021, 13, DOI 10.3390/pharmaceutics13050696 (2021)

Quantification of biomarker functionality predicts patient outcomes

B. Larijani, J. Miles, S. G. Ward, P. J. Parker

Br. J. Cancer 2021, 124, 1618 (2021)

Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

C. Caillat, D. Guilligay, J. Torralba, N. Friedrich, J. L. Nieva, A. Trkola, C. J. Chipot, F. L. Dehez, W. Weissenhorn

Elife 2021, 10, DOI 10.7554/ELIFE.65005 (2021)

Palladium-mediated synthesis and biological evaluation of C-10b substituted Dihydropyrrolo[1,2-b]isoquinolines as antileishmanial agents

I. Barbolla, L. Hernández-Suárez, V. Quevedo-Tumailli, D. Nocedo-Mena, S. Arrasate, M. A. Dea-Ayuela, H. González-Díaz, N. Sotomayor, E. Lete

Eur. J. Med. Chem. 2021, 220, DOI 10.1016/j.ejmech.2021.113458 (2021)

Mitochondrial membrane tension governs fission

D. Mahecic, L. Carlini, T. Kleele, A. Colom, A. Goujon, S. Matile, A. Roux, S. Manley

Cell Rep. 2021, 35, DOI 10.1016/j.celrep.2021.108947 (2021)

Molecular docking, SAR analysis and biophysical approaches in the study of the antibacterial activity of ceramides isolated from Cissus incisa

D. Nocedo-Mena, S. Arrasate, E. Garza-González, V. M. Rivas-Galindo, A. Romo-Mancillas, C. R. Munteanu, N. Sotomayor, E. Lete, I. Barbolla, C. A. Martín, M. del Rayo Camacho-Corona

Bioorg. Chem. 2021, 109, DOI 10.1016/j.bioorg.2021.104745 (2021)

Characterizing the lone pair⋯π–hole interaction in complexes of ammonia with perfluorinated arenes

W. Li, I. Usabiaga, C. Calabrese, L. Evangelisti, A. Maris, L. B. Favero, S. Melandri

Phys. Chem. Chem. Phys. 2021, 23, 9121 (2021)

Rotational spectroscopic study and astronomical search for propiolamide in Sgr B2(N)

E. R. Alonso, L. Kolesnikova, A. Belloche, S. Mata, R. T. Garrod, A. Jabri, I. León, J.-C. Guillemin, H. S. P. Muller, K. M. Menten, K. M. Menten, J. L. Alonso

Astron. Astrophys. 2021, 647, DOI 10.1051/0004- 6361/202040211 (2021)

(r)HDL in theranostics: how do we apply HDL\\\'s biology for precision medicine in atherosclerosis management?

K. B. Uribe, A. Benito-Vicente, C. Martin, F. Blanco-Vaca, N. Rotllan

Biomater. Sci. 2021, 9, 3185 (2021)

Molecular mechanisms of lipotoxicity-induced pancreatic β-cell dysfunction

A. Benito-Vicente, S. Jebari-Benslaiman, U. Galicia-Garcia, A. Larrea-Sebal, K. B. Uribe, C. Martin

Molecular Mechanisms of Lipotoxicity-Induced Pancreatic β-Cell Dysfunction, (2021)

Fluorine Labeling of Nanoparticles and In Vivo 19F Magnetic Resonance Imaging

Juan Manuel Arango, Daniel Padro, Jorge Blanco, Sonia Lopez-Fernandez, Pilar Castellnou, Palmira Villa-Valverde, Jesús Ruiz-Cabello, Abraham Martin, and Mónica Carril

ACS Appl. Mater. Interfaces 2021, 13, 11, 12941–12949 (2021)

VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases

A. M. V Queiroz, J. W. F. Oliveira, C. J. Moreno, D. M. A. Guérin, M. S. Silva

Vaccines 2021, 9, 1 (2021)

Exploring the Maze of Cycloserine Conformers in the Gas Phase Guided by Microwave Spectroscopy and Quantum Chemistry

E. R. Alonso, M. Fuse, I. León, C. Puzzarini, J. L. Alonso, V. Barone

J. Phys. Chem. A 2021, 125, 10, 2121–2129 (2021)

Virion structure and in vitro genome release mechanism of dicistrovirus Kashmir bee virus

L. Mukhamedova, T. Füzik, J. Novácek, D. Hrebík, A. Pridal, G. A. Marti, D. M. A. Guérin, P. Plevka

J. Virol. 2021, 95, DOI 10.1128/JVI.01950-20. (2021)

Lipoprotein metabolism in familial hypercholesterolemia

K. Chemello, J. García-Nafría, A. Gallo, C. Martín, G. Lambert, D. Blom

J. Lipid Res. 2021, 62, DOI 10.1016/J.JLR.2021.100062 (2021)

Single-molecule conformational dynamics of viroporin ion channels regulated by lipid-protein interactions

E. Largo, M. Queralt-Martín, P. Carravilla, J. L. Nieva, A. Alcaraz

Bioelectrochemistry 2021, 137, DOI 10.1016/j.bioelechem.2020.107641. (2021)

Use of pore-forming toxins to study co-translocational protein folding

A. De la Torre-Cabrera, D. Rodriguez-Larrea

Use of Pore-Forming Toxins to Study Co-Translocational Protein Folding, 2021. (2021)

Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH

Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, David Fernández-Ramos, Diego Sáenz de Urturi, Jessica J Gruskos, Pablo Fernández-Tussy, Sofía Lachiondo-Ortega, Irene González-Recio, Rubén Rodríguez-Agudo, Virginia Gutiérrez-de-Juan, Begoña Rodríguez-Iruretagoyena, Marta Varela-Rey, Paula Gimenez-Mascarell, María Mercado-Gomez, Beatriz Gómez-Santos, Carmen Fernandez-Rodriguez, Fernando Lopitz-Otsoa, Maider Bizkarguenaga, Sibylle Dames, Ute Schaeper, Franz Martin, Guadalupe Sabio, Paula Iruzubieta, Javier Crespo, Patricia Aspichueta, Kevan H-Y Chu, Daniela Buccella, César Martín, Teresa Cardoso Delgado, Luis Alfonso Martínez-Cruz, María Luz Martínez-Chantar

J Hepatol .;75(1):34-45. doi: 10.1016/j.jhep.2021.01.043 (2021)

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Klionsky, D.J., [...], Alonso, A., Goni, F.M., Hervas, J.H., Montes, L.R., [...] Tong, C.K.

Autophagy. 2021 Feb 8:1-382. doi: 10.1080/15548627.2020.1797280 (2021)

Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

A. Insausti, E. R. Alonso, B. Tercero, J. I. Santos, C. Calabrese, N. Vogt, F. Corzana, J. Demaison, J. Cernicharo, E. J. Cocinero

J. Phys. Chem. Lett. 2021, 12, 1352 (2021)

The interaction of Aβ42 peptide in monomer, oligomer or fibril forms with sphingomyelin/cholesterol/ganglioside bilayers

H. Ahyayauch, M. Masserini, F. M. Goñi, A. Alonso

Int. J. Biol. Macromol. 2021, 168, 611 (2021)

Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

Aran Insausti, Elena R. Alonso, Belen Tercero, José I. Santos, Camilla Calabrese, Natalja Vogt, Francisco Corzana, Jean Demaison, Jose Cernicharo, and Emilio J. Cocinero

J. Phys. Chem. Lett. 2021, 12, 4, 1352–1359 (2021)

BioMetAll: Identifying Metal-Binding Sites in Proteins from Backbone Preorganization

J.-E. Sánchez-Aparicio, L. Tiessler-Sala, L. Velasco-Carneros, L. Roldán-Martín, G. Sciortino, J.-D. Maréchal

J. Chem. Inf. Model. 2021, 61, 311 (2021)

The role of the intramolecular interactions in the structural behavior of biomolecules: Insights from rotational spectroscopy

Alonso ER, León I, Alonso JL.

Developments in Physical & Theoretical Chemistry, Pages 93-141 (2021) doi: 10.1016/B978-0-12-817586-6.00004-9. (2021)

The interaction of Aβ42 peptide in monomer, oligomer or fibril forms with sphingomyelin/cholesterol/ganglioside bilayers

Ahyayauch H, Masserini M, Goñi FM, Alonso A.

Int J Biol Macromol. S0141-8130(20)35037-6. doi: 10.1016/j.ijbiomac.2020.11.112. (2021)

Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope

I. de la Arada, J. Torralba, I. Tascón, A. Colom, I. Ubarretxena-Belandia, J. L. R. Arrondo, B. Apellániz, J. L. Nieva

Sci. Rep. 2021, 11, DOI 10.1038/s41598-020-80156-w. (2021)

Oligonucleotide-Directed Protein Threading Through a Rigid Nanopore

Celaya G, Rodriguez-Larrea D.

Methods Mol Biol. 2186:135-144. (2021) doi: 10.1007/978-1-0716-0806-7_10. (2021)

Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/tacrolimus formulations

Hidalgo A, Garcia-Moutona C, Autilio C, Carravilla P, Orellana G, Islam MN, Bhattacharya J, Bhattacharya S, Cruz A, Pérez-Gil J.

Journal of Controlled Release 329, 205–222 (2021)

Phase-selective staining of model and cell membranes, lipid droplets and lipoproteins with fluorescent solvatochromic pyrene probes

Sot J, Esnal I, Monasterio BG, León-Irra R, Niko Y, Goñi FM, Klymchenko A, Alonso A.

Biochim Biophys Acta Biomembr. 1863(1):183470. (2021) doi: 10.1016/j.bbamem.2020.183470. (2021)

Single-molecule conformational dynamics of viroporin ion channels regulated by lipid-protein interactions

Largo E, Queralt-Martín M, Carravilla P, Nieva JL, Alcaraz A.

Bioelectrochemistry. 137:107641. (2020) doi: 10.1016/j.bioelechem.2020.107641. (2021)

Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

I. E. Sampaio-Dias, J. E. Rodríguez-Borges, V. Yáñez-Pérez, S. Arrasate, J. Llorente, J. M. Brea, H. Bediaga, D. Vinã, M. I. Loza, O. Caamanõ, X. Garciá-Mera, H. González-Diáz

ACS Chem. Neurosci. 2021, 12, 203 (2021)

IFPTML mapping of nanoparticle antibacterial activity vs. pathogen metabolic networks

B. Ortega-Tenezaca, H. González-Díaz

Nanoscale 2021, 13, 1318 (2021)

Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV-1 Env Clustering

Nieto-Garai JA, Arboleya A, Otaegi S, Chojnacki J, Casas, J, Fabrias G, Contreras FX, Krausslich HG, Lorizate M.

Advanced Science. 2003468. (2020) doi: 10.1002/advs.202003468 (2020)

BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque

Alloza I, Salegi A, Mena J, Navarro RT, Martin C, Aspichueta P, Salazar LM, Carpio JU, Cagigal PD, Vega R, Triviño JC, Freijo MDM, Vandenbroeck K.

Int J Mol Sci. 21(24):E9387. (2020) doi: 10.3390/ijms21249387. (2020)

Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

Alaimo A, Lorenzoni M, Ambrosino P, Bertossi A, Bisio A, Macchia A, Zoni E, Genovesi S, Cambuli F, Foletto V, De Felice D, Soldovieri MV, Mosca I, Gandolfi F, Brunelli M, Petris G, Cereseto A, Villarroel A, Thalmann G, Carbone FG, Kruithof-de Julio M, Barbareschi M, Romanel A, Taglialatela M, Lunardi A.

Cell Death Dis. 11(12):1039. (2020) doi: 10.1038/s41419-020-03256-5. (2020)

Boundary versus enabling conditions for the origins of life: Comment on \\

Ruiz-Mirazo K.

Phys Life Rev. 34-35:96-98. (2020) doi: 10.1016/j.plrev.2020.06.001 (2020)

β-Amyloid (1-42) peptide adsorbs but does not insert into ganglioside-containing phospholipid membranes in the liquid-disordered state: modelling and experimental studies

Ahyayauch H, García-Arribas AB, Masserini ME, Pantano S, Goñi FM, Alonso A.

Int J Biol Macromol. 164:2651-2658. (2020) doi: 10.1016/j.ijbiomac.2020.08.165. (2020)

Structural insights into Pseudomonas aeruginosaType six secretion system exported effector 8

González-Magaña A, Sainz-Polo MÁ, Pretre G, Çapuni R, Lucas M, Altuna J, Montánchez I, Fucini P, Albesa-Jové D.

J Struct Biol. 212(3):107651. (2020) doi: 10.1016/j.jsb.2020.107651. (2020)

PTML Multi-Label Algorithms: Models, Software, and Applications

Ortega-Tenezaca B, Quevedo-Tumailli V, Bediaga H, Collados J, Arrasate S, Madariaga G, Munteanu CR, Cordeiro MNDS, González-Díaz H.

Curr Top Med Chem. 20(25):2326-2337. (2020) doi: 10.2174/1568026620666200916122616. (2020)

Characterization of monolayers and liposomes that mimic lipid composition of HeLa cells

Botet-Carreras A, Montero MT, Sot J, Domènech Ò, Borrell JH

Colloids Surf B Biointerfaces. 196:111288. (2020) doi: 10.1016/j.colsurfb.2020.111288 (2020)

A Multi-Objective Approach for Anti-Osteosarcoma Cancer Agents Discovery through Drug Repurposing

Cabrera-Andrade A, López-Cortés A, Jaramillo-Koupermann G, González-Díaz H, Pazos A, Munteanu CR, Pérez-Castillo Y, Tejera E.

Pharmaceuticals (Basel). 13(11):409. (2020) doi: 10.3390/ph13110409. (2020)

miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression

Benito-Vicente A, Uribe KB, Rotllan N, Ramírez CM, Jebari-Benslaiman S, Goedeke L, Canfrán-Duque A, Galicia-García U, Saenz De Urturi D, Aspichueta P, Suárez Y, Fernández-Hernando C, Martín C.

Int J Mol Sci. 21(22):8675. (2020) doi: 10.3390/ijms21228675. (2020)

A Compression Engine to Coordinate Tissue Elongation in the Embryo

Trubuil É, Solon J.

Dev Cell. 55(3):256-258. (2020) doi: 10.1016/j.devcel.2020.10.013. (2020)

Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town

Huijgen R, Blom DJ, Hartgers ML, Chemello K, Benito-Vicente A, Uribe KB, Behardien Z, Blackhurst DM, Brice BC, Defesche JC, de Jong AG, Jooste RJ, Ratanjee BD, Solomon GAE, Wolmarans KH, Hovingh GK, Martin C, Lambert G, Marais AD.

Arterioscler Thromb Vasc Biol. ATVBAHA120314482. (2020) doi: 10.1161/ATVBAHA.120.314482. Online ahead of print. (2020)

Exploring polar headgroup interactions between sphingomyelin and ceramide with infrared spectroscopy

de la Arada I, González-Ramírez EJ, Alonso A, Goñi FM, Arrondo JR.

Sci Rep. 10(1):17606. (2020) doi: 10.1038/s41598-020-74781-8. (2020)

Perturbation-Theory Machine Learning (PTML) Multilabel Model of the ChEMBL Dataset of Preclinical Assays for Antisarcoma Compounds

Cabrera-Andrade A, López-Cortés A, Munteanu CR, Pazos A, Pérez-Castillo Y, Tejera E, Arrasate S, González-Díaz H.

ACS Omega. 5(42):27211-27220. (2020) doi: 10.1021/acsomega.0c03356. (2020)

Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies

Rujas E, Cui H, Sicard T, Semesi A, Julien JP.

Nat Commun. 11(1):5066. (2020) doi: 10.1038/s41467-020-18828-4. (2020)

Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition

Jebari-Benslaiman S, Uribe KB, Benito-Vicente A, Galicia-Garcia U, Larrea-Sebal A, Alloza I, Vandenbroeck K, Ostolaza H, Martín C.

Biomedicines. 8(10):E373. (2020) doi: 10.3390/biomedicines8100373 (2020)

Therapeutic Pretargeting with Gold Nanoparticles as Drug Candidates for Boron Neutron Capture Therapy

Feiner IVJ, Pulagam KR, Gomez-Vallejo V, Zamacola K, Baz Z, Caffarel MM, Lawrie CH, Ruiz-de-Angulo A, Carril M, Llop J.

Part Part Syst Char. 2000200 (2020) doi: 10.1002/ppsc.202000200 (2020)

Preformulation Studies of a Stable PTEN-PDZ Lipopeptide Able to Cross an In Vitro Blood-Brain-Barrier Model as a Potential Therapy for Alzheimer\\\'s Disease

Lalatsa A, Sun Y, Gamboa JI, Knafo S.

Pharm Res, 37(10):183. (2020) doi: 10.1007/s11095-020-02915-8. (2020)

Center for Astrobiology: Toward the RNA-World in the Interstellar Medium-Detection of Urea and Search of 2-Amino-oxazole and Simple Sugars

Jiménez-Serra I, Martín-Pintado J, Rivilla VM, Rodríguez-Almeida L, Alonso Alonso ER, Zeng S, Cocinero EJ, Martín S, Requena-Torres M, Martín-Domenech R, Testi L.

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Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions

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Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition

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Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins

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Multimodal 19F‐NMR dopamine detection and imaging with a nanoparticle‐based displacement assay

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Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants

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Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S

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Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly

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Mobile genetic elements and antibiotic resistance in mine soil amended with organic wastes

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The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

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Exploring the role of genome and structural ions in preventing viral capsid collapse during dehydration

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The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria

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Quantifying intracellular equilibrium dissociation constants using single-channel time-resolved FRET

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Functional variants in the LRRK2 gene confer shared effects on risk for Crohn\\\'s disease and Parkinson\\\'s disease

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Mobile genetic elements and antibiotic resistance in mine soil amended with organic wastes

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Model-based image analysis of a tethered Brownian fibre for shear stress sensing

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Membrane insertion of the BAX core, but not latch domain, drives apoptotic pore formation

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Structural Snapshots of alpha-1,3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases

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Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge

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Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

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Identification and in vitro characterization of two new PCSK9 Gain of Function variants found in patients with Familial Hypercholesterolemia

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Editorial on the Special Issue: Molecules and Cognition

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Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria

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Purification and characterization of the colicin A immunity protein in detergent micelles

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Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

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Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels

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Structure-Related Roles for the Conservation of the HIV-1 Fusion Peptide Sequence Revealed by Nuclear Magnetic Resonance

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Biofilm-Forming Clinical Staphylococcus Isolates Harbor Horizontal Transfer and Antibiotic Resistance Genes

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Environmental parameters altered by climate change affect the activity of soil microorganisms involved in bioremediation

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Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

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Peptides Acting as Cognitive Enhancers

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Plasmid-Mediated Bioaugmentation for the Bioremediation of Contaminated Soils

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Last issue of journal of chemical biology

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Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes

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Effects of HIV-1 gp41-Derived Virucidal Peptides on Virus-like Lipid Membranes

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Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state

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Coating Graphene Oxide with Lipid Bilayers Greatly Decreases Its Hemolytic Properties

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The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

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Uncoupling TORC2 from AGC kinases inhibits tumour growth

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Apoptotic foci at mitochondria: in and around Bax pores

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Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo

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Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function

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Analysis of LDLR variants from homozygous FH patients carrying multiple mutations in the LDLR gene

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A High Resolution Study of Dynamic Changes of Ce2O3 and CeO2 Nanoparticles in Complex Environmental Media

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Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

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Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

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Polyamine-RNA-membrane interactions: From the past to the future in biology

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Permeability-driven selection in a semi-empirical protocell model: the roots of prebiotic systems evolution

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2D IR Correlation Spectroscopy in the Determination of Aggregation and Stability of KH Domain GXXG Loop Peptide in the Presence and Absence of Trifluoroacetate

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Complex Effects of 24:1 Sphingolipids in Membranes Containing Dioleoylphosphatidylcholine and Cholesterol

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