Ana R. Viguera

Staff scientist (CSIC)

She earned his BS in Chemistry and MS in Biochemistry and the PhD from the University of the Basque Country (UPV/EHU) Shee did her postdoctoral research at the EMBL (Heidelberg, Germany) working on protein folding. Her research has been focused on membrane protein folding.

Publications

The Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution

Morante K, Bellomio A, Viguera AR, González-Mañas JM, Tsumoto K, Caaveiro JMM.

Toxins (Basel).11(7). pii: E401. (2019) doi: 10.3390/toxins11070401. (2019)
Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

Y Cabrera, L Dublang, JA Fernández-Higuero, D Albesa-Jové, M Lucas, AR Viguera, ME Guerin, JMG Vilar, A Muga , F Moro.

J Mol Biol ;431(2):444-461. doi: 10.1016/j.jmb.2018.11.026 (2019)
Purification and characterization of the colicin A immunity protein in detergent micelles

A. Metola, A.M. Bouchet, M. Alonso-Marino, T. Diercks, L. Maler, F.M. Goni and A.R. Viguera

Biochim Biophys Acta 1859, 2181-2192 doi: 10.1016/j.bbamem.2017.08.007 (2017)
Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea

Morante K, Caaveiro JM, Viguera AR, Tsumoto K, González-Mañas JM

FEBS Lett. 589:1840-6 (2015)
High-melting lipid mixtures and the origin of detergent-resistant membranes studied with temperature-solubilization diagrams.

J. Sot, M.M. Manni, A.R. Viguera, V. Castañeda, A. Cano, C. Alonso, D. Gil, M. Valle, A. Alonso and F.M. Goñi.

Biophys J. 107, 2828-2837 (2014).
Sphingosine induces the aggregation of imine-containing peroxidized vesicles.

N. Jiménez-Rojo, A.R. Viguera, M.I. Collado, K.H. Sims, C. Constance, K. Hill, W.A. Shaw, F.M. Goñi and A. Alonso.

Biochim. Biophys. Acta 1838, 2071-2077 (2014).
Membrane permeabilization induced by sphingosine: effect of negatively charged lipids.

N. Jiménez-Rojo, J. Sot, A.R. Viguera, M.I. Collado, A. Torrecillas, J.C. Gómez-Fernández, F.M. Goñi and A. Alonso.

Biophys. J. 106 2577–2584 (2014).
The C-terminal transmembrane domain of human phospholipid scramblase 1 is essential for the protein flip-flop activity and Ca2+-binding.

L. Sánchez-Magraner, I.M. Posada, N. Andraka, F.X. Contreras, A.R. Viguera, D.M. Guérin, J.L.R. Arrondo, H.L. Monaco and F.M. Goñi.

J Membr Biol. 247, 155-165 (2014).
Membrane partitioning of the pore-forming domain of Colicin A. role of the hydrophobic helical hairpin.

I.L. Bermejo, C. Arnulphi, A. Ibáñez de Opakua, M. Alonso-Mariño, F.M. Goñi and A.R. Viguera.

Biophys. J. 105, 1432-1443 (2013).
NMR assignment and backbone dynamics of the pore-forming domain of colicin A.

A. Ibañez de Opakua, T. Diercks, A.R. Viguera and F.J. Blanco.

Biomol NMR assign DOI 10.1007/s12104-009-9202-4 (2010).