The R&D programs of BIOFISIKA are grouped in two main Research Lines and five Research Sublines. This rational combination of independent group abilities and skills in supplementary fields contributes to reduce scientific dispersion and undertake more ambitious and complex research projects. The distribution of the research groups in the different Research Lines respond to the will of BIOFISIKA to create a unique Research and Training program able to exploit all the singularities present in the Center, fostering the complementarities and synergies of the different groups.
Click the boxes below to go through the different Research Lines for each program
BIOFISIKA Research line organisation
Fluorinated nanostructures as tools for imaging and delivery (FluoroNanoTools)
The research of the group is mainly focused on the use of fluorinated nanostructures as enabling tools to learn about dynamic biological processes. On the one hand, we use fluorine as a label that can be tuned for the design of OFF/ON or Smart contrast agents based on 19F MRI or as a reporter ...
Biomolecules, Molecular recognition, Astrochemistry
Our research focus on the accurate structural characterization of biomolecules and molecules of astrophysical interest and its molecular interactions by state-of-the-art spectroscopic techniques in the gas phase. Our research encompasses different methodologies ranging from the microwave ...
Bionanotechnology as a Tool for Drug Delivery
Drug delivery plays a crucial role in the development on new therapeutic strategies and it is mainly determined by the transport across the membrane of the target cell. In this field nanotechnology can offer innovative approaches. Our research group is working on lipid-based drug ...
Structural Glycobiology
Glycans are not only one of the major components of the cell but also are essential molecules that modulate a variety of important biological processes in all living organisms. The structural diversity od glycans is particularly relevant in molecular recognition events including cell-cell, ...
X-Ray Crystallography of Membrane Proteins
This research program has two main and complementary focuses: structure-function of integral membrane proteins and structure-based drug discovery & design. The projects developed in this program are focused on determining the crystal structure of membrane proteins and, the development ...
Virus Research and Development
Learning about the structure of macromolecules of biological interest (enzymes, receptors, large molecular aggregates such as viruses) enables the mechanisms of the biochemical functions they perform to be interpreted. Protein crystallography, currently the most advanced and powerful technique ...
Membrane Protein Folding and Stability. Structural Motif Engineering and Design
Protein folding has been the subject of intensive research. Well-designed combinations of experimental and computational studies are enabling folding to be followed at atomic resolution, with the result that general rules are emerging. This insight, however, pertains to water-soluble proteins ...