Publications
2014
N-Nervonoylsphingomyelin (C24:1) prevents lateral heterogeneity in cholesterol-containing membranes.
Biophys. J. 106 2606–2616 (2014).
Organizational requirements for multicellular autonomy: insights from a comparative case study.
Biol. Philos. 29, 851-884 (2014).
Advantages and versatility of fluorescence-based methodology to characterize the functionality of LDLR and class mutation assignment
. PLoS One. 9(11):e112677. doi: 10.1371/journal.pone.0112677 (2014).
Entropy of leukemia on multidimensional morphological and molecular landscapes.
Phys. Rev. X 4, 021038 (2014).
High-throughput time-resolved FRET reveals Akt/PKB activation as a poor prognostic marker in breast cancer.
Cancer Res. 74, 4983-4995 (2014).
Lamellar gel (L?) phases of ternary lipid composition containing ceramide and cholesterol.
Biophys. J. 106, 621-630 (2014).
Membrane permeabilization induced by sphingosine: effect of negatively charged lipids.
Biophys. J. 106 2577–2584 (2014).
Pore-forming activity of pestivirus p7 in a minimal model system supports genus-specific viroporin function.
Antiviral Res. 101, 30-36 (2014).
2013
Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes.
Acta Cryst. D69, 1965–1980 (2013).
The onset of Triton X-100 solubilization of sphingomyelin/ceramide bilayers: effects of temperature and composition.
Chem. Phys. Lipids. 167-168, 57-61 (2013).
Screening and evaluation of small organic molecules as ClpB inhibitors and potential antimicrobials.
J. Med. Chem. 56, 7177-7189 (2013).
A biophysicist in the kitchen.
Flavour, 2:7 (2013).
Probing the biophysical interplay between a viral genome and its capsid.
Nat Chem. 5, 502-509 (2013).
Hofmeister ions control protein dynamics.
Biochim. Biophys. Acta. 1830, 4564-4572 (2013).
Free Fructose is conformationally locked
J. Am. Chem. Soc., 135, 2845-1852 (2013)
A computational module assembled from different protease family motifs identifies PI PLC from Bacillus cereus as a putative prolyl peptidase with a serine protease scaffold.
PLoS One, 8(8):e70923. doi: 10.1371/journal.pone.0070923 (2013).
Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus.
PLoS Pathog. 9:e1003108. doi: 10.1371/journal.ppat.1003108 (2013).
Effects of chronic and acute lead treatments on the biophysical properties of erythro- cyte membranes, and a comparison with model membranes.
FEBS Open Bio 3, 212–217 (2013).
Definir vida: un ejercicio constructivo.
SEBBM 175, 3-6 (2013).
Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells.
Biochim. Biophys. Acta General Subjects 1830: 4872-4884 (2013).
Fourier-space TEM reconstructions with symmetry adapted functions for all rotational point groups.
J. Struct. Biol. 182, 87-92 (2013).
Calpain-mediated processing of adenylate cyclase toxin generates a cytosolic soluble catalytically active NTerminal domain.
PLoS One 8, Issue 6 | e67648 (2013).
Cooperativity between calmodulin-binding sites in Kv7.2 channels.
J. Cell Sci. 126, 244-253 (2013).
Structural insights into the chaperone activity of the 40-kDa heat shock protein DnaJ: binding and remodeling of a native substrate.
J. Biol. Chem. 288, 15065-15074 (2013).
The use of dansyl-calmodulin to study interactions with channels and other proteins.
Methods Mol. Biol. 998, 217-231 (2013).
Membrane partitioning of the pore-forming domain of Colicin A. role of the hydrophobic helical hairpin.
Biophys. J. 105, 1432-1443 (2013).
The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the m-current.
J Neurosci. 33, 2684-2696 (2013).
The mechanism of detergent solubilization of lipid bilayers.
Biophys. J. 105, 289–299 (2013).
Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers.
Chem Phys Lipids. 166, 12-17 (2013).
Molecular techniques for dicistrovirus detection without RNA extraction or purification.
Biomed Res Int. 2013, ID 218593. doi: 10.1155/2013/218593 (2013).
Exploiting tertiary structure through local folds for crystallographic phasing.
Nat. Methods 10, 1099-1101 (2013).
Detergent solubilization of lipid bilayers: a balance of driving forces.
Trends Biochem Sci. 38, 85-93 (2013).
Recognition of intermolecular G-quadruplexes by full length nucleophosmin. Effect of a leukaemia-associated mutation.
FEBS Lett. 587, 2254–2259 (2013).
Geometric catalysis of membrane fission driven by flexible dynamin rings.
Science 339, 1433-1436 (2013).
Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the entry route.
PLoS One 8, 1-14 (2013).
Comparative lipidomics analysis of HIV-1 particles and their producer cell membrane in different cell lines.
Cell Microbiol. 15, 292-304 (2013).
Synthetic biology: Challenging life in order to grasp, use, or extend it.
Biological Theory 8: 376–382 (2013)
Exploration for Triatoma virus (TrV) infection in laboratory-reared triatomines of Latin America: a collaborative study.
Int. J. Trop. Insect Sci., 33, 294–304 (2013).
Crystal structure and functional mechanism of a human antimicrobial membrane channel.
Proc Natl Acad Sci USA. 110, 4586-4591 (2013).
Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.
Acta Cryst. D69, 2146–2156 (2013).