2021

• Quantification of biomarker functionality predicts patient outcomes.

  Br J Cancer 124, 1618–1620 (2021) doi: 10.1038/s41416-021-01291-3

• Lyophilized, Thermostable Spike or RBD Immunogenic Liposomes Induce Protective Immunity Against SARS-CoV-2 in Mice.

  Sci. Adv. 7, eabj1476, (2021) doi: 10.1126/sciadv.abj1476

• Bacteriophage PRD1 as a nanoscaffold for drug loading

  Nanoscale, 2021,13, 19875-19883, (2021) doi: 10.1039/D1NR04153C

• (r)HDL in theranostics: how do we apply HDL's biology for precision medicine in atherosclerosis management?

  Biomater. Sci., 2021,9, 3185-3208, (2021) doi: 10.1039/D0BM01838D

• Predicting Metabolic Reaction Networks with Perturbation-Theory Machine Learning (PTML) Models

  Current Topics in Medicinal Chemistry, 21, 9, 819-827, (2021) doi: 10.2174/1568026621666210331161144

• Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA.

  Sci Adv. 2021 Oct 15;7(42):eabj4565. doi: 10.1126/sciadv.abj4565.. PMID: 34652941

• Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size.

  The FASEB Journal, 35:e21657, (2021) doi: 10.1096/fj.202001879RR

• VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases.

  Vaccines 2021, 9(3), 220; (2021) doi: 10.3390/vaccines9030220

• Single-aminoacid discrimination in proteins with homogeneous nanopore sensors and neural networks

  Biosensors and Bioelectronics, 180, 2021,113108, (2021) doi: 10.1016/j.bios.2021.113108

• FORTIS: a live-cell assay to monitor AMPA receptors using pH-sensitive fluorescence tags.

  Transl Psychiatry 11, 324 (2021) doi:10.1038/s41398-021-01457-w

• Dimeric Rhodopsin R135L mutant-transducin complex sheds light on misfunctions leading to Retinitis pigmentosa.

  J. Phys. Chem. B 2021, 125, 47, 12958–12971, (2021) doi: 10.1021/acs.jpcb.1c06348

• NMR identification of a conserved Drp1 cardiolipin-binding motif essential for stress- induced mitochondrial fission.

  Proceedings of the National Academy of Sciences Jul 2021, 118 (29) e2023079118, (2021) doi: 10.1073/pnas.2023079118

• Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

  eLife 2021;10:e65005, (2021) doi: 10.7554/eLife.65005

• CHO/LY-B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes.

  The FASEB Journal, 35:e21657 (2021) doi: 10.1096/fj.202001879RR

• Prediction of Anti-Glioblastoma Drug-Decorated Nanoparticle Delivery Systems Using Molecular Descriptors and Machine Learning.

  Int. J. Mol. Sci. 2021, 22(21), 11519; (2021) doi: 10.3390/ijms222111519

• Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts

  Gastroenterology 2021;161:1179–1193, (2021) doi: 10.1053/j.gastro.2021.06.064

• Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope.

  Sci Rep 11, 1278 (2021) doi: 10.1038/s41598-020-80156-w

• Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

  ACS Chem. Neurosci. 2021, 12, 1, 203–215, (2021) doi: 10.1021/acschemneuro.0c00687

• All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species.

  Proceedings of the National Academy of Sciences Sep 2021, 118 (36) e2105548118, (2021) doi: 10.1073/pnas.2105548118

• MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDL receptor Missense Variants

  Atherosclerosis 331 (2021) e3, (2021) doi: 10.1016/j.atherosclerosis.2021.06.013

• Minimal metabolism: a key concept to investigate the origins and nature of biological systems.

  BioEssays, 43, e2100103, (2021) doi: 10.1002/bies.202100103

• A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants.

  Int. J. Mol. Sci. 2021, 22(24), 13602; (2021) doi: 10.3390/ijms222413602

• Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH

  J. Hepatol. 2021, 75, 34–45, (2021) doi: 10.1016/j.jhep.2021.01.043

• Reliably quantifying the evolving worldwide dynamic state of the COVID-19 outbreak from death records, clinical parametrization, and demographic data.

  Sci Rep 11, 19952 (2021) doi:10.1038/s41598-021-99273-1

• BioMetAll: Identifying Metal-Binding Sites in Proteins from Backbone Preorganization.

  J. Chem. Inf. Model. 2021, 61, 1, 311–323, (2021) doi: 10.1021/acs.jcim.0c00827

• Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach.

  Cancers 2021, 13(12), 2936; (2021) doi: 10.3390/cancers13122936

• Lipoprotein(a) in heterozygous familial hypercholesterolemia. Influence of the causative gene and type of mutation.

  Atherosclerosis, Available online 23 August 2021 In Press, Corrected Proof (2021) doi: 10.1016/j.atherosclerosis.2021.08.009

• Laboratory Detection of Cyanoacetic Acid: A Jet-cooled Rotational Study.

  The Astrophysical Journal, 915:76 (8pp), (2021) doi: 10.3847/1538-4357/ac013f

• Measuring In-Vivo Protein Turnover and Exchange in Macromolecular Assemblies

  STAR Protocols 2, 100800, September 17, 2021 (2021) doi: 10.1016/j.xpro.2021.100800

• Shape of Testosterone.

  J. Phys. Chem. Lett. 2021, 12, 29, 6983–6987, (2021) doi: 10.1021/acs.jpclett.1c01743

• Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure

  Front. Synaptic Neurosci. 13:683290, (2021) doi: 10.3389/fnsyn.2021.683290

• Degradation of Drug Delivery Nanocarriers and Payload Release: A Review of Physical Methods for Tracing Nanocarrier Biological Fate.

  Pharmaceutics 2021, 13(6), 770; (2021) doi: 10.3390/pharmaceutics13060770

• LDLR variants functional characterization: contribution for variant classification

  Atherosclerosis 329 (2021) 14–21, (2021) doi: 10.1016/j.atherosclerosis.2021.06.001

• Tissue mechanics in morphogenesis: Active control of tissue material properties to shape living organisms

  Cells & Development, 203777 (2021) https://doi.org/10.1016/j.cdev.2022.203777

• Ascertaining the initiation of epidemic resurgences: an application to the COVID-19 second surges in Europe and the Northeast United States.

  R. Soc. open sci., 8: 210773, (2021) doi:1 0.1098/rsos.210773

• Editorial: ‘Inter-identities' in Life, Mind, and Society.

  Front. Psychol. 12:704772, (2021) doi: 10.3389/fpsyg.2021.704772

• The role of the intramolecular interactions in the structural behavior of biomolecules: Insights from rotational spectroscopy

  Developments in Physical & Theoretical Chemistry, Intra- and Intermolecular Interactions Between Non-covalently Bonded Species, 2021, 93-141, (2021) doi: 10.1016/B978-0-12-817586-6.00004-9

• Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

  Hepatology (2021), Volume 75, Issue 3 p. 550-566, doi.org/10.1002/hep.32149

• Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease.

  Sci Rep 11, 23315 (2021) doi: 10.1038/s41598-021-02432-7

• Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

  J. Phys. Chem. Lett. 2021, 12, 4, 1352–1359, (2021) doi: 10.1021/acs.jpclett.0c03050