Publications
2016
Lipid geometry and bilayer curvature modulate LC3/GABARAP-mediated model autophagosomal elongation
Biophys J. 110, 411–422 (2016)
Molecular basis of membrane association by the phosphatidylinositol mannosyltransferase PimA enzyme from mycobacteria
J Biol Chem. 291, 13955-13963. (2016)
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate
Sci Rep. 1; 6:38167. doi: 10.1038/srep38167 (2016)
Thermotropic properties of ceramides in aqueous or lipidic environments
Book article CRC Press, Boca Raton, FL, USA, pp. 137-151 (2016)
Functional organizacion of the HIV lipid envelope
Sci Rep 6 34190. doi: 10.1038/srep34190 (2016)
Ion channel activity of the CSFV p7 viroporin in surrogates of the ER lipid bilayer
Biochim Biophys Acta.1858, 30-37 (2016)
A crowdsourcing approach to developing and assessing prediction algorithms for AML prognosis
PloS Comput Biol. 12:e1004890. doi: 10.1371/journal.pcbi.1004890 (2016)
A celular reporter to evaluate CRM1 nuclear export activity: functional analysis of the cancer-related mutant E571K
Cell Mol Life Sci. 73, 4685-4699 (2016)
The p.Leu167del mutation in APOE gene causes autosomal dominant hypercholesterolemia by down-regulation of LDL receptor expression in hepatocytes
J Clin Endocrinol Metab. 101, 2113-2121 (2016)
Identification of a membrane-bound prepore species clarifies the lytic mechanism of actinoporins
J Biol Chem. 291, 19210-19219 (2016)
Crowding modulates the conformation, affinity, and activity of the components of the bacterial disaggregase machinery
J Mol Biol. 428, 2474-2487 (2016)
The use of targeted exome sequencing in genetic diagnosis of young patients with severe hypercholesterolemia
Sci Rep. 6, 36823 doi. 10.1038/srep36823 (2016)
Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
Nat Commun. 11, 10906. doi: 10.1038/ncomms10906 (2016)
2015
Characterization of the first PCSK9 gain of function homozygote
J Am Coll Cardiol. 66:2152-4 (2015)
ClpB dynamics is driven by its ATPase cycle and regulated by the DnaK system and substrate proteins
Biochem J. 466:561-70 (2015)
The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating
Biophys J. 109:529-41 (2015)
Geometry of membrane fission
Chem Phys Lipids. 185, 129-140 (2015)
A combinatorial approach to the design of vaccines
J. Math. Biol. 70, 1327-1358 (2015)
Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis
J Diabetes Res. 2015:515307 (2015)
The importance of an integrated analysis of clinical, molecular, and functional data for the genetic diagnosis of familial hypercholesterolemia
Genet Med. doi: 10.1038/gim.2015.14 (2015)
C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake
Biochim Biophys Acta Biomembranes 1850:1656-70 (2015)
Solvation and hydration of the ceramide headgroup in a non-polar solution.
J. Phys. Chem. B 119, 128?139. (2015).
The Use of Liposomes to Shape Epitope Structure and Modulate Immunogenic Responses of Peptide Vaccines Against HIV MPER
Adv Protein Chem Str Biol 99:15-54 (2015)
Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly de-stabilizing epileptogenic mutation
J Cell Sci. 28:4014-23 (2015)
Fluorescent polyene ceramide analogues as membrane probes
Langmuir. 2015 Mar 3;31(8):2484-92
A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase
Angew Chem Int Edit 17:9898-9902 Q1 13/157 (2015)
Cognitive enhancement. Pharmacologic, environmental and genetic factors.
Academic Press, London, 2015, pp. 392 (2015)
Modulation of the chaperone DnaK allosterism by the nucleotide exchange factor GrpE
J Biol Chem. 290:10083-92 (2015)
Solid lipid nanoparticles for delivery of Calendula officinalis extract
Colloid Surface B. 135:18-26 (2015)
Low pH modulates the macroorganization and thermal stability of PSII supercomplexes in grana membranes
Biophys. J. 108, 844–853 (2015)
Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea
FEBS Lett. 589:1840-6 (2015)
Functional characterization and classification of frequent low-density lipoprotein receptor variants.
Hum Mutat. 36, 129-141 (2015).
End-product diacylglycerol enhances the activity of PI-PLC through changes in membrane domain structure
Biophys J. 108:1672-82 (2015)
Lipids that determine detergent resistance of MDCK cell membrane fractions
Chem Phys Lipids. 191:68-74 (2015)
Histones cause aggregation and fusion of lipid vesicles containing phosphatidylinositol-4-phosphate
Biophys J. 2015 Feb 17;108(4):863-71
Antimicrobial peptides: has their time arrived?
Future Microbiol. 10:1-4 (2015)
Secondary structure reshuffling modulates glycosyltransferase function at the membrane.
Nat Chem Biol. 11, 16-18 (2015).
Triatoma virus recombinant VP4 protein induces membrane permeability through dynamic pores
J. Virol. 89(8):4645-4654 (2015)
Lipidic nanovesicles stabilize suspensions of metal oxide nanoparticles
Chem Phys Lipids. 191:84-90 (2015)
Activity-associated effect of LDL receptor missense variants located in the cysteine-rich repeats.
Atherosclerosis 238, 304-312 (2015).