| Biofisika

Access all the 2010-2011-2012 publications through the next link.

Public 2010-2012

Access all the publications since 2013 on (included) through the next links.

Nonlinear material and ionic transport through membrane nanotubes

D. V Ivchenkov, P. I. Kuzmin, T. R. Galimzyanov, A. V Shnyrova, P. V Bashkirov, V. A. Frolov

Biochim. Biophys. Acta - Biomembr. 2021, 1863, DOI 10.1016/j.bbamem.2021.183677 (2021)

Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells

L. M. Nolan, A. K. Cain, T. Clamens, R. C. D. Furniss, E. Manoli, M. A. Sainz-Polo, G. Dougan, D. Albesa- Jové, J. Parkhill, D. A. I. Mavridou, D. A. I. Mavridou, A. Filloux

Nat. Microbiol. 2021, DOI 10.1038/s41564-021-00950-8. (2021)

Antibodies response induced by recombinant virus-like particles from Triatoma virus and chimeric antigens from Trypanosoma cruzi

A. M. V. Queiroz, Y. A. Yanshina, E. T. da Silva Rodrigues, F. L. N. Santos, P. A. F. Celedon, S. Maheshwari, S. B. Gabelli, C. S. P. Rubio, A. Durana, D. M. A. Guérin, M. S. Silva

Vaccine 2021, 39, 4723 (2021)

Super-Resolution Microscopy Using a Bioorthogonal-Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in Living Cells

M. Lorizate, O. Terrones, J. A. Nieto-Garai, I. Rojo-Bartolomé, D. Ciceri, O. Morana, J. Olazar-Intxausti, A. Arboleya, A. Martin, M. Szynkiewicz, J. B. de la Serna, F.-X. Contreras

Small Methods 2021, DOI 10.1002/smtd.202100430 (2021)

In Vitro Cellular Uptake Studies of Self-Assembled Fluorinated Nanoparticles Labelled with Antibodies

M. Atabakhshi-Kashi, M. Carril, H. Mahdavi, W. J. Parak, C. Carrillo-Carrion, K. Khajeh

Nanomaterials 2021, 11, DOI 10.3390/nano11081906 (2021)

Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison

J. Carrasco-Pujante, C. Bringas, I. Malaina, M. Fedetz, L. Martínez, G. Pérez-Yarza, M. D. Boyano, M. , Berdieva, A. Goodkov, J. I. López, S. Knafo, I. M. De la Fuente

Front. Microbiol. 2021, 12, DOI 10.3389/fmicb.2021.707086 (2021)

Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective size

D. G. Bullón, K. B. Uribe, J. Amuategi, C. Martín, H. Ostolaza

FEBS J. 2021, DOI 10.1111/febs.16107 (2021)

Predicting Metabolic Reaction Networks with Perturbation-Theory Machine Learning (PTML) Models

K. Diéguez-Santana, G. M. Casañola-Martin, J. R. Green, B. Rasulev, H. González-Díaz

Curr. Top. Med. Chem. 2021, 21, 819 (2021)

The Role of Non-Covalent Interactions on Cluster Formation: Pentamer, Hexamers and Heptamer of Difluoromethane

C. Calabrese, B. Temelso, I. Usabiaga, N. A. Seifert, F. J. Basterretxea, G. Prampolini, G. C. Shields, B. H. Pate, L. Evangelisti, E. J. Cocinero

Angew. Chemie - Int. Ed. 2021, 60, 16894 (2021)

LDLR variants functional characterization: Contribution to variant classification

A. C. Alves, S. Azevedo, A. Benito-Vicente, R. Graça, U. Galicia-Garcia, P. Barros, P. Jordan, C. Martin, M. Bourbon

Atherosclerosis 2021, 329, 14 (2021)

Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts

M. Bortolomeazzi, M. R. Keddar, L. Montorsi, A. Acha-Sagredo, L. Benedetti, D. Temelkovski, S. Choi, N. Petrov, K. Todd, P. Wai, J. Spencer, F. D. Ciccarelli

Gastroenterology 2021, DOI 10.1053/j.gastro.2021.06.064. (2021)

Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers

E. Rujas, I. Kucharska, Y. Z. Tan, S. Benlekbir, H. Cui, T. Zhao, G. A. Wasney, P. Budylowski, F. Guvenc, J. C. Newton, B. Treanor, J.-P. Julien

Nat. Commun. 2021, 12, DOI 10.1038/s41467-021-23825-2 (2021)

Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain

D. J. López, J. A. Rodríguez, S. Bañuelos

Int. J. Mol. Sci. 2021, 22, DOI 10.3390/ijms22126308 (2021)

Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach

L. Dublang, J. Underhaug, M. I. Flydal, L. Velasco-Carneros, J.-D. Maréchal, F. Moro, M. D. Boyano, A. Martinez, A. Muga

Cancers (Basel). 2021, 13, DOI 10.3390/cancers13122936 (2021)

Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/tacrolimus formulations

A. Hidalgo, C. Garcia-Mouton, C. Autilio, P. Carravilla, G. Orellana, M. N. Islam, J. Bhattacharya, S. Bhattacharya, A. Cruz, J. Pérez-Gil

J. Control. Release 2021, 329, 205 (2021)

The emerging landscape of single-molecule protein sequencing technologies

J. A. Alfaro, P. Bohländer, M. Dai, M. Filius, C. J. Howard, X. F. van Kooten, S. Ohayon, A. Pomorski, S. Schmid, A. Aksimentiev, A. Meller, C. Joo

Nat. Methods 2021, 18, 604 (2021)

Oligonucleotide-Directed Protein Threading Through a Rigid Nanopore

G. Celaya, D. Rodriguez-Larrea

Oligonucleotide-Directed Protein Threading through a Rigid Nanopore, 2021. (2021)

FORTIS: a live-cell assay to monitor AMPA receptors using pH-sensitive fluorescence tags

M. Calleja-Felipe, M. N. Wojtas, M. Diaz-González, D. Ciceri, R. Escribano, A. Ouro, M. Morales, S. Knafo

Transl. Psychiatry 2021, 11, DOI 10.1038/s41398-021-01457-w (2021)

SR-B1, a Key Receptor Involved in the Progression of Cardiovascular Disease: A Perspective from Mice and Human Genetic Studies

Gracia-Rubio Irene, Martín César, Civeira Fernando, Cenarro Ana

Biomedicines 2021, 9, DOI 10.3390/biomedicines9060612 (2021)

An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel

J. Urrutia, A. Aguado, C. Gomis-Perez, A. Muguruza-Montero, O. R. Ballesteros, J. Zhang, E. Nuñez, C. Malo, H. J. Chung, A. Leonardo, A. Bergara, A. Villarroel

BMC Biol. 2021, 19, DOI 10.1186/s12915-021- 01040-1. (2021)

Degradation of Drug Delivery Nanocarriers and Payload Release: A Review of Physical Methods for Tracing Nanocarrier Biological Fate

P. M. Perrigue, R. A. Murray, A. Mielcarek, A. Henschke, S. E. Moya

Pharmaceutics 2021, 13, DOI 10.3390/pharmaceutics13060770 (2021)

CHO/LY-B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes

B. G. Monasterio, N. Jiménez-Rojo, A. B. García-Arribas, H. Riezman, F. M. Goñi, A. Alonso

FASEB J. 2021, 35, DOI 10.1096/fj.202001879RR. (2021)

Single-aminoacid discrimination in proteins with homogeneous nanopore sensors and neural networks

D. Rodriguez-Larrea

Biosens. Bioelectron. 2021, 180, DOI 10.1016/j.bios.2021.113108. (2021)

Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure

M. D. González, A. Buberman, M. Morales, I. Ferrer, S. Knafo

Front. Synaptic Neurosci. 2021, 13, DOI 10.3389/fnsyn.2021.683290 (2021)

Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells

Y. Vado, G. Puras, M. Rosique, C. Martin, J. L. Pedraz, S. Jebari-Benslaiman, M. M. de Pancorbo, J. Zarate, G. P. de Nanclares

Pharmaceutics 2021, 13, DOI 10.3390/pharmaceutics13050696 (2021)

Quantification of biomarker functionality predicts patient outcomes

B. Larijani, J. Miles, S. G. Ward, P. J. Parker

Br. J. Cancer 2021, 124, 1618 (2021)

Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

C. Caillat, D. Guilligay, J. Torralba, N. Friedrich, J. L. Nieva, A. Trkola, C. J. Chipot, F. L. Dehez, W. Weissenhorn

Elife 2021, 10, DOI 10.7554/ELIFE.65005 (2021)

Palladium-mediated synthesis and biological evaluation of C-10b substituted Dihydropyrrolo[1,2-b]isoquinolines as antileishmanial agents

I. Barbolla, L. Hernández-Suárez, V. Quevedo-Tumailli, D. Nocedo-Mena, S. Arrasate, M. A. Dea-Ayuela, H. González-Díaz, N. Sotomayor, E. Lete

Eur. J. Med. Chem. 2021, 220, DOI 10.1016/j.ejmech.2021.113458 (2021)

Mitochondrial membrane tension governs fission

D. Mahecic, L. Carlini, T. Kleele, A. Colom, A. Goujon, S. Matile, A. Roux, S. Manley

Cell Rep. 2021, 35, DOI 10.1016/j.celrep.2021.108947 (2021)

Molecular docking, SAR analysis and biophysical approaches in the study of the antibacterial activity of ceramides isolated from Cissus incisa

D. Nocedo-Mena, S. Arrasate, E. Garza-González, V. M. Rivas-Galindo, A. Romo-Mancillas, C. R. Munteanu, N. Sotomayor, E. Lete, I. Barbolla, C. A. Martín, M. del Rayo Camacho-Corona

Bioorg. Chem. 2021, 109, DOI 10.1016/j.bioorg.2021.104745 (2021)

Characterizing the lone pair⋯π–hole interaction in complexes of ammonia with perfluorinated arenes

W. Li, I. Usabiaga, C. Calabrese, L. Evangelisti, A. Maris, L. B. Favero, S. Melandri

Phys. Chem. Chem. Phys. 2021, 23, 9121 (2021)

Rotational spectroscopic study and astronomical search for propiolamide in Sgr B2(N)

E. R. Alonso, L. Kolesnikova, A. Belloche, S. Mata, R. T. Garrod, A. Jabri, I. León, J.-C. Guillemin, H. S. P. Muller, K. M. Menten, K. M. Menten, J. L. Alonso

Astron. Astrophys. 2021, 647, DOI 10.1051/0004- 6361/202040211 (2021)

(r)HDL in theranostics: how do we apply HDL\\\'s biology for precision medicine in atherosclerosis management?

K. B. Uribe, A. Benito-Vicente, C. Martin, F. Blanco-Vaca, N. Rotllan

Biomater. Sci. 2021, 9, 3185 (2021)

Molecular mechanisms of lipotoxicity-induced pancreatic β-cell dysfunction

A. Benito-Vicente, S. Jebari-Benslaiman, U. Galicia-Garcia, A. Larrea-Sebal, K. B. Uribe, C. Martin

Molecular Mechanisms of Lipotoxicity-Induced Pancreatic β-Cell Dysfunction, (2021)

Fluorine Labeling of Nanoparticles and In Vivo 19F Magnetic Resonance Imaging

Juan Manuel Arango, Daniel Padro, Jorge Blanco, Sonia Lopez-Fernandez, Pilar Castellnou, Palmira Villa-Valverde, Jesús Ruiz-Cabello, Abraham Martin, and Mónica Carril

ACS Appl. Mater. Interfaces 2021, 13, 11, 12941–12949 (2021)

VLP-Based Vaccines as a Suitable Technology to Target Trypanosomatid Diseases

A. M. V Queiroz, J. W. F. Oliveira, C. J. Moreno, D. M. A. Guérin, M. S. Silva

Vaccines 2021, 9, 1 (2021)

Exploring the Maze of Cycloserine Conformers in the Gas Phase Guided by Microwave Spectroscopy and Quantum Chemistry

E. R. Alonso, M. Fuse, I. León, C. Puzzarini, J. L. Alonso, V. Barone

J. Phys. Chem. A 2021, 125, 10, 2121–2129 (2021)

Virion structure and in vitro genome release mechanism of dicistrovirus Kashmir bee virus

L. Mukhamedova, T. Füzik, J. Novácek, D. Hrebík, A. Pridal, G. A. Marti, D. M. A. Guérin, P. Plevka

J. Virol. 2021, 95, DOI 10.1128/JVI.01950-20. (2021)

Lipoprotein metabolism in familial hypercholesterolemia

K. Chemello, J. García-Nafría, A. Gallo, C. Martín, G. Lambert, D. Blom

J. Lipid Res. 2021, 62, DOI 10.1016/J.JLR.2021.100062 (2021)

Single-molecule conformational dynamics of viroporin ion channels regulated by lipid-protein interactions

E. Largo, M. Queralt-Martín, P. Carravilla, J. L. Nieva, A. Alcaraz

Bioelectrochemistry 2021, 137, DOI 10.1016/j.bioelechem.2020.107641. (2021)

Use of pore-forming toxins to study co-translocational protein folding

A. De la Torre-Cabrera, D. Rodriguez-Larrea

Use of Pore-Forming Toxins to Study Co-Translocational Protein Folding, 2021. (2021)

Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH

Jorge Simón, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, David Fernández-Ramos, Diego Sáenz de Urturi, Jessica J Gruskos, Pablo Fernández-Tussy, Sofía Lachiondo-Ortega, Irene González-Recio, Rubén Rodríguez-Agudo, Virginia Gutiérrez-de-Juan, Begoña Rodríguez-Iruretagoyena, Marta Varela-Rey, Paula Gimenez-Mascarell, María Mercado-Gomez, Beatriz Gómez-Santos, Carmen Fernandez-Rodriguez, Fernando Lopitz-Otsoa, Maider Bizkarguenaga, Sibylle Dames, Ute Schaeper, Franz Martin, Guadalupe Sabio, Paula Iruzubieta, Javier Crespo, Patricia Aspichueta, Kevan H-Y Chu, Daniela Buccella, César Martín, Teresa Cardoso Delgado, Luis Alfonso Martínez-Cruz, María Luz Martínez-Chantar

J Hepatol .;75(1):34-45. doi: 10.1016/j.jhep.2021.01.043 (2021)

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Klionsky, D.J., [...], Alonso, A., Goni, F.M., Hervas, J.H., Montes, L.R., [...] Tong, C.K.

Autophagy. 2021 Feb 8:1-382. doi: 10.1080/15548627.2020.1797280 (2021)

Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

A. Insausti, E. R. Alonso, B. Tercero, J. I. Santos, C. Calabrese, N. Vogt, F. Corzana, J. Demaison, J. Cernicharo, E. J. Cocinero

J. Phys. Chem. Lett. 2021, 12, 1352 (2021)

The interaction of Aβ42 peptide in monomer, oligomer or fibril forms with sphingomyelin/cholesterol/ganglioside bilayers

H. Ahyayauch, M. Masserini, F. M. Goñi, A. Alonso

Int. J. Biol. Macromol. 2021, 168, 611 (2021)

Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

Aran Insausti, Elena R. Alonso, Belen Tercero, José I. Santos, Camilla Calabrese, Natalja Vogt, Francisco Corzana, Jean Demaison, Jose Cernicharo, and Emilio J. Cocinero

J. Phys. Chem. Lett. 2021, 12, 4, 1352–1359 (2021)

BioMetAll: Identifying Metal-Binding Sites in Proteins from Backbone Preorganization

J.-E. Sánchez-Aparicio, L. Tiessler-Sala, L. Velasco-Carneros, L. Roldán-Martín, G. Sciortino, J.-D. Maréchal

J. Chem. Inf. Model. 2021, 61, 311 (2021)

The role of the intramolecular interactions in the structural behavior of biomolecules: Insights from rotational spectroscopy

Alonso ER, León I, Alonso JL.

Developments in Physical & Theoretical Chemistry, Pages 93-141 (2021) doi: 10.1016/B978-0-12-817586-6.00004-9. (2021)

Phase-selective staining of model and cell membranes, lipid droplets and lipoproteins with fluorescent solvatochromic pyrene probes

Sot J, Esnal I, Monasterio BG, León-Irra R, Niko Y, Goñi FM, Klymchenko A, Alonso A.

Biochim Biophys Acta Biomembr. 1863(1):183470. (2021) doi: 10.1016/j.bbamem.2020.183470. (2021)

Single-molecule conformational dynamics of viroporin ion channels regulated by lipid-protein interactions

Largo E, Queralt-Martín M, Carravilla P, Nieva JL, Alcaraz A.

Bioelectrochemistry. 137:107641. (2020) doi: 10.1016/j.bioelechem.2020.107641. (2021)

Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

I. E. Sampaio-Dias, J. E. Rodríguez-Borges, V. Yáñez-Pérez, S. Arrasate, J. Llorente, J. M. Brea, H. Bediaga, D. Vinã, M. I. Loza, O. Caamanõ, X. Garciá-Mera, H. González-Diáz

ACS Chem. Neurosci. 2021, 12, 203 (2021)

IFPTML mapping of nanoparticle antibacterial activity vs. pathogen metabolic networks

B. Ortega-Tenezaca, H. González-Díaz

Nanoscale 2021, 13, 1318 (2021)