Access all the 2010-2011-2012 publications through the next link.
Access all the publications since 2013 on (included) through the next links.
When Humans Met Superbugs: Strategies to Tackle Bacterial Resistances to Antibiotics
Bravo A, Ruiz-Cruz S, Alkorta I, Espinosa
M. Biomol Concepts. 9(1):216-226. doi: 10.1515/bmc-2018-0021. (2018)
Characterization of the Intrinsic Phospholipase A1 Activity of Bordetella pertussis Adenylate Cyclase Toxin
González-Bullón D, Martín C, Ostolaza H.
Toxins (Basel) 10(12). pii: E514. doi: 10.3390/toxins10120514. (2018)
The fatty acids of sphingomyelins and ceramides in mammalian tissues and cultured cells: Biophysical and physiological implications
MM Manni, J Sot, E Arretxe, R Gil-Redondo, JM Falcón-Pérez, D Balgoma, C Alonso, FM Goñi, A Alonso.
Chem Phys Lipids. 217:29-34. doi:10.1016/j.chemphyslip.2018.09.010 (2018)
p.(Asp47Asn) and p.(Thr62Met): non deleterious LDL receptor missense variants functionally characterized in vitro
A Benito-Vicente, H Siddiqi, KB Uribe, S Jebari, U Galicia-Garcia, A Larrea-Sebal, M Stef, H Ostolaza, L Palacios, C Martin.
Sci Rep. 8(1):16614. doi: 10.1038/s41598-018-34715-x (2018)
Omega-3 polyunsaturated fatty acids do not fluidify bilayers in the liquid-crystalline state
A De Santis, Y Varela, J Sot, G D\'Errico, FM Goñi, A Alonso.
Sci Rep. 8(1):16240. doi: 10.1038/s41598-018-34264-3 (2018)
Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease
A Benito-Vicente, KB Uribe, S Jebari, U Galicia-Garcia, H Ostolaza, C Martin.
Int J Mol Sci.19(11). pii: E3426. doi: 10.3390/ijms19113426. (2018)
Molecular Characterization of the Viroporin Function of Foot-and-Mouth Disease Virus Nonstructural Protein 2B
DP Gladue, E Largo, I de la Arada, VM Aguilella, A Alcaraz, JLR Arrondo, LG Holinka, E Brocchi, E Ramirez-Medina, EA Vuono, KA Berggren, C Carrillo, JL Nieva, MV Borca.
J Virol. 92(23). pii: e01360-18. doi: 10.1128/JVI.01360-18. (2018)
Millimeter-wave spectroscopy and modeling of 1,2-butanediol
A. Vigorito, C. Calabrese, S. Melandri, A. Caracciolo,S. Mariotti, A. Giannetti, M. Massardi, and A. Maris
Astronomy & Astrophysics. doi: 10.1051/0004-6361/201833489. (2018)
Conformational entropy of a single peptide controlled under force governs protease recognition and catalysis
ME Guerin, G Stirnemann, D Giganti.
PNAS. doi:10.1073/pnas.1803872115. (2018)
Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition
Benito-Vicente A, Uribe KB, Siddiqi H, Jebari S, Galicia-Garcia U, Larrea-Sebal A, Cenarro A, Stef M, Ostolaza H, Civeira F, Palacios L, Martin C.
PLoS One. 13(10):e0204771. doi: 10.1371/journal.pone.0204771. (2018)
Design and validation of an open-source modular Microplate Photoirradiation System for high-throughput photobiology experiments
Katz S, Backeris P, Merck C, Suprun M, D\\\'Souza S, Bishop DF, Desnick RJ, Moore K, Ubarretxena-Belandia I, Lemischka IR.
PLoS One 13(10):e0203597. doi:10.1371/journal.pone.0203597. eCollection 2018. (2018)
Soft and dispersed interface-rich aqueous systems that promote and guide chemical reactions
Serrano-Luginbühl S, Ruiz-Mirazo K, Ostaszewski R, Gallou F, Walde P.
Nature Reviews Chemistry 2, 306–327. doi: 10.1038/s41570-018-0042-6 (2018)
Clearly Detectable, Kinetically Restricted Solid−Solid Phase Transition in cis-Ceramide Monolayers
Fanani ML, Busto JV, Sot J, Abad JL, Fabrías G, Saiz L, Vilar JMG, Goñi FM, Maggio B, Alonso A.
Langmuir; 34(39):11749-11758. doi: 10.1021/acs.langmuir.8b02198. (2018)
Further evidence of novel APOB mutations as a cause of familial hypercholesterolaemia
AC Alves, A Benito-Vicente, AM Medeiros, K Reeves, C Martin, M Bourbon.
Atherosclerosis 277:448-456. doi: 10.1016/j.atherosclerosis.2018.06.819 (2018)
Rotational spectroscopy update for the newly identified atmospheric ozone depleter CF3CCl3
Kisiel Z, Pszczółkowski L, Białkowska-Jaworska E, Jaworski M, Uriarte I, Basterretxea FJ, Cocinero EJ.
Journal of Molecular Spectroscopy 352, 1–9 (2018)
Competing Dispersive Interactions: From Small Energy Differences to Large Structural Effects in Methyl Jasmonate and Zingerone
I Uriarte, A Insausti, EJ Cocinero, A Jabri, I Kleiner, H Mouhib, I Alkorta.
J Phys Chem Lett. 9(20):5906-5914. doi: 10.1021/acs.jpclett.8b02339 (2018)
Lack of correlation between surface expression and currents in epileptogenic AB-calmodulin binding domain Kv7.2 potassium channel mutants
Alaimo A, Etxeberria A, Gómez-Posada JC, Gomis-Perez C, Fernández-Orth J, Malo C, Villarroel A.
Channels (Austin) 12, 299-310. doi: 10.1080/19336950.2018.1511512 (2018)
Data on links between structural and functional prokaryotic diversity in long-term sewage sludge amended soil
J Urra, I Alkorta, I Mijangos, C Garbisu.
Data Brief. 20:1787-1796. doi: 10.1016/j.dib.2018.09.025. eCollection 2018 (2018)
Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure
Nieto-Garai JA, Glass B, Bunn C, Giese M, Jennings G, Brankatschk B, Agarwal S, Börner K, Contreras FX, Knölker HJ, Zankl C, Simons K, Schroeder C, Lorizate M, Kräusslich HG.
Front Immunol. 2018 ;9:1983. doi: 10.3389/fimmu.2018.01983. eCollection 2018. (2018)
Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum
Gladue DP, Largo E, Holinka LG, Ramirez-Medina E, Vuono EA, Berggren KA, Risatti GR, Nieva JL, Borca MV.
Viruses. 2018 ;10(9). pii: E460. doi: 10.3390/v10090460. (2018)
Coupled Transmembrane Substrate Docking and Helical Unwinding in Intramembrane Proteolysis of Amyloid Precursor Protein
Clemente N, Abdine A, Ubarretxena-Belandia I, Wang C.
Sci Rep. 8, 12411. doi: 10.1038/s41598-018-30015-6 (2018)
Lateral plasma membrane compartmentalization links protein function and turnover
Busto JV, Elting A, Haase D, Spira F, Kuhlman J, Schäfer-Herte M, Wedlich-Söldner R.
EMBO J. 37. pii: e99473. doi: 10.15252/embj.201899473 (2018)
Acute depletion of diacylglycerol from the cis-Golgi affects localized nuclear envelope morphology during mitosis
Chung GHC, Domart MC, Peddie C, Mantell J, Mclaverty K, Arabiotorre A, Hodgson L, Byrne RD, Verkade P, Arkill K, Collinson LM, Larijani B.
J Lipid Res. 59, 1402-1413. doi: 10.1194/jlr.M083899 (2018)
The 2018 biomembrane curvature and remodeling roadmap
Bassereau P, Jin R,. Baumgart T, Deserno M , Dimova R, Frolov VA, Bashkirov PV, Grubmuller H, Jahn R, Risselada HJ, Johannes L, Kozlov MM, Lipowsky R, Pucadyil TJ, Zeno WF, Stachowiak JC, Stamou D, Breuer A, Lauritsen L, Simon C, Voth GA, Weikl TR.
Journal Of Physics D-Applied Physics 51, 34, 343001. doi: 10.1088/1361-6463/aacb98 (2018)
Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions
Alaimo A, Villarroel A.
Biomolecules 8, pii: E57. doi: 10.3390/biom8030057 (2018)
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition
Iris A. Bermejo, Imanol Usabiaga, Ismael Compañón, Jorge Castro-López, Aran Insausti, José A. Fernández, Alberto Avenoza, Jesús H. Busto, Jesús Jiménez-Barbero, Juan L. Asensio, Jesús M. Peregrina, Gonzalo Jiménez-Osés, Ramón Hurtado-Guerrero, Emilio J. Cocinero, and Francisco Corzana
J. Am. Chem. Soc., 2018, 140 (31), pp 9952–9960 DOI: 1 0.1021/jacs.8b04801 (2018)
Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins
Etxaniz A, González-Bullón D, Martín C, Ostolaza H.
Toxins 10, pii: E234. doi: 10.3390/toxins10060234 (2018)
Multimodal 19F‐NMR dopamine detection and imaging with a nanoparticle‐based displacement assay
L. Gabrielli, M. Carril, D. Padro and F. Mancin.
Chemistry: A European Journal, 2018 (accepted article, in press). DOI: 10.1002/chem.201802482 (2018)
Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants
Benito-Vicente A, Uribe KB, Jebari S, Galicia-Garcia U, Ostolaza H, Martin C.
Int J Mol Sci 19, pii: E1676. doi: 10.3390/ijms19061676 (2018)
Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S
Trastoy B, Klontz E, Orwenyo J, Marina A, Wang LX, Sundberg EJ, Guerin ME
Nat Commun. 9, 1874. doi: 10.1038/s41467-018-04300-x (2018)
Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells
Ahyayauch H, García-Arribas AB, Sot J, González-Ramírez EJ, Busto JV, Monasterio BG, Jiménez-Rojo N, Contreras FX, Rendón-Ramírez A, Martin C, Alonso A, Goñi FM.
Sci Rep. 8, 7456. doi: 10.1038/s41598-018-25905-8 (2018)
Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly
Viso JF, Belelli P, Machado M, González H, Pantano S, Amundarain MJ, Zamarreño F, Branda MM, Guérin DMA, Costabel MD.
PLoS Comput Biol. 14, e1006082. doi: 10.1371/journal.pcbi.1006082 (2018)
Mobile genetic elements and antibiotic resistance in mine soil amended with organic wastes
Garbisu C, Garaiyurrebaso O, Lanzén A, Álvarez-Rodríguez I, Arana L, Blanco F, Smalla K, Grohmann E, Alkorta I.
Sci Total Environ. 2018;621:725-733. doi:10.1016/j.scitotenv.2017.11.221 (2018)
The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading
Baulies A, Montero J, Matías N, Insausti N, Terrones O, Basañez G, Vallejo C, Conde de La Rosa L, Martinez L, Robles D, Morales A, Abian J, Carrascal M, Machida K, Kumar DBU, Tsukamoto H, Kaplowitz N, Garcia-Ruiz C, Fernández-Checa JC.
Redox Biol. 2018;14:164-177. doi: 10.1016/j.redox.2017.08.022 (2018)
Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate
Fernández-Higuero JA, Aguado A, Perales-Calvo J, Moro F, Muga A.
Sci Rep. 2018;8(1):5796. doi: 10.1038/s41598-018-24140-5 (2018)
DNA-binding miniproteins based on Zinc Fingers. Assessment of the interaction using nanopores
Rodríguez J, Learte-Aymamí S, Mosquera J, Celaya G, Rodríguez-Larrea D, Vázquez ME and Mascareñas JL.
Chemical Science. 2018. doi: 10.1039/C7SC05441F (2018)
Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis
Brown MC, Abdine A, Chavez J, Schaffner A, Torres-Arancivia C, Lada B, JiJi RD, Osman R, Cooley JW, Ubarretxena-Belandia I.
Biophys J. 2018;114(7):1579-1589. doi: 10.1016/j.bpj.2018.01.043 (2018)
Polarized two-photon photoselection in EGFP: Theory and experiment
Masters TA, Marsh RJ, Blacker TS, Armoogum DA, Larijani B, Bain AJ.
J Chem Phys. 2018;148(13):134311. doi: 10.1063/1.5011642 (2018)
Time-resolved stimulated emission depletion and energy transfer dynamics in two-photon excited EGFP
Masters TA, Robinson NA, Marsh RJ, Blacker TS, Armoogum DA, Larijani B, Bain AJ.
J Chem Phys. 2018;148(13):134312. doi: 10.1063/1.5011643 (2018)
The Physical Properties of Ceramides in Membranes
Alonso A, Goñi FM.
Annu Rev Biophys. 2018. doi: 10.1146/annurev-biophys-070317-033309 (2018)
From phytoremediation of soil contaminants to phytomanagement of ecosystem services in metal contaminated sites
Burges A, Alkorta I, Epelde L, Garbisu C.
Int J Phytoremediation. 2018;20(4):384-397. doi: 10.1080/15226514.2017.1365340 (2018)
Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions
Wang S, Mao Y, Narimatsu Y, Ye Z, Tian W, Goth CK, Lira-Navarrete E, Pedersen NB, Benito-Vicente A, Martin C, Uribe KB, Hurtado-Guerrero R, Christoffersen C, Seidah NG, Nielsen R, Christensen EI, Hansen L, Bennett EP, Vakhrushev SY, Schjoldager KT, Clausen H.
J Biol Chem. 2018. pii: jbc.M117.817981. doi:10.1074/jbc.M117.817981 (2018)
Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage
Manni MM, Tiberti ML, Pagnotta S, Barelli H, Gautier R, Antonny B. ,
Elife. 2018;7. pii: e34394. doi: 10.7554/eLife.34394 (2018)
Coupling proteins in Type IV secretion
M. Llosa and I. Alkorta
“Type IV Secretion in Gram-negative and Gram-positive bacteria”, (Backert, S. y Grohmann, E., editors) ISBN 978-3-319-75240-2, pág. 143-168, (2018). Capítulo de libro. Título de la serie: Current topics in Microbiology and Immunology (Springer eds) 413, 143-168 https://doi.org/10.1007/978-3-319-75241-9. (2018)
Exploring the role of genome and structural ions in preventing viral capsid collapse during dehydration
Martín-González, N. Guérin-Darvas, S., Durana, A., Martí, G.A., Guérin, D.M.A, De Pablo Gomez, P.J.
J Phys Condens Matter. 2018;30(10):104001. doi: 10.1088/1361-648X/aaa944 (2018)
Shapes, Dynamics, and Stability of β-Ionone and Its Two Mutants Evidenced by High-Resolution Spectroscopy in the Gas Phase
Uriarte I, Melandri S, Maris A, Calabrese C, Cocinero EJ
J Phys Chem Lett. 2018;9(7):1497-1502. doi: 10.1021/acs.jpclett.8b00256 (2018)
Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel
Bernardo-Seisdedos G, Nuñez E, Gomis-Perez C, Malo C, Villarroel Á, Millet O.
Proc Natl Acad Sci U S A. 2018;115(10):2395-2400. doi:10.1073/pnas.1800235115. Erratum in: Proc Natl Acad Sci U S A. 2018;115(15):E3599. doi: 10.1073/pnas.1804137115 (2018)
Phase behavior of palmitoyl and egg sphingomyelin
Arsov Z, Gonzalez-Ramirez EJ, Goni FM, Tristram-Nagle S, Nagle J.
Chemistry and Physics of Lipids 2018 (2018)
Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds
Oakes V, Torralba J, Rujas E, Nieva JL, Domene C, Apellaniz B.
. Biochim Biophys Acta. 2018;1860(6):1259-1271. doi: 10.1016/j.bbamem.2018.02.019 (2018)
Reply to Masin et al: To be or not to be a phospholipase A
Ostolaza H.
Proc Natl Acad Sci U S A. 2018;115(11):E2491. doi: 10.1073/pnas.1801017115 (2018)
Peptides Acting as Cognitive Enhancers
Asua D, Bougamra G, Calleja-Felipe M, Morales M, Knafo S.
Neuroscience. 2018;370:81-87. doi: 10.1016/j.neuroscience.2017.10.002 (2018)
Editorial on the Special Issue: Molecules and Cognition
Barco A, Knafo S.
Neuroscience. 2018;370:1-3. doi: 10.1016/j.neuroscience.2017.11.003 (2018)
Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions
Rujas E, Leaman DP, Insausti S, Ortigosa-Pascual L, Zhang L, Zwick MB, Nieva JL.
J Virol. 2018;92(8). pii: e02249-17. doi: 10.1128/JVI.02249-17 (2018)
The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria
Tersa M, Raich L, Albesa-Jové D, Trastoy B, Prandi J, Gilleron M, Rovira C, Guerin ME.
ACS Chem Biol. 2018;13(1):131-140. doi:10.1021/acschembio.7b00578 (2018)
Determinants of population responses to environmental fluctuations
Vilar JMG, Rubi JM.
Sci Rep. 2018;8(1):887. doi: 10.1038/s41598-017-18976-6 (2018)
Mutation-induced changes of transmembrane pore size revealed by combined ion-channel conductance and single vesicle permeabilization analyses
Largo E, Gladue DP, Torralba J, Aguilella VM, Alcaraz A, Borca MV, Nieva JL.
Biochim Biophys Acta. 2018;1860(5):1015-1021. doi: 10.1016/j.bbamem (2018)
HIV antivirals: targeting the functional organization of the lipid envelope
Carravilla P, Nieva, JL.
Future Virology. 2018; 13, 129-140. doi: 10.2217/fvl-2017-0114 (2018)
Quantifying intracellular equilibrium dissociation constants using single-channel time-resolved FRET
G. De las Heras-Martinez, J. Andrieu, B. Larijani, J. Requejo-Isidro
Journal of Biophotonics 11, 1. Doi: 10.1002/jbio.201600272 (2018)
Functional variants in the LRRK2 gene confer shared effects on risk for Crohn\\\'s disease and Parkinson\\\'s disease
Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, Ruane D, Gettler K, Chen E, Li D, Schiff ER, Pontikos N, Barzilai N, Brant SR, Bressman S, Cheifetz AS, Clark LN, Daly MJ, Desnick RJ, Duerr RH, Katz S, Lencz T, Myers RH, Ostrer H, Ozelius L, Payami H, Peter Y, Rioux JD, Segal AW, Scott WK, Silverberg MS, Vance JM, Ubarretxena-Belandia I, Foroud T, Atzmon G, Pe\'er I, Ioannou Y, McGovern DPB, Yue Z, Schadt EE, Cho JH, Peter I. ,
Sci Transl Med. 2018 Jan 10;10(423). pii: eaai7795. doi: 10.1126/scitranslmed.aai7795. PubMed PMID: 29321258; PubMed Central PMCID: PMC6028002 (2018)