| Biofisika

T. Lissek, M. Adams, J. Adelman, E. Ahissar, M. Akaaboune, H. Akil, M. al\'Absi, F. Arain, J.C. Arango-Lasprilla, D. Atasoy, J. Avila, A. Badawi, H. Bading, A.M. Baig, J. Baleriola, C. Belmonte, I. Bertocchi, H. Betz, C. Blakemore, O. Blanke, P. Boehm-Sturm, T. Bonhoeffer, P. Bonifazi, N. Brose, P. Campolongo, T. Celikel, C.C. Chang, T.Y. Chang, A. Citri, H.T. Cline, J.M. Cortes, K. Cullen, K. Dean, J.M. Delgado-Garcia, M. Desroches, J.F. Disterhoft, J.E. Dowling, A. Draguhn, S.F. El-Khamisy, A. El Manira, S.A. Enam, J.M. Encinas, A. Erramuzpe, J.A. Esteban, I. Fariñas, E. Fischer, I. Fukunaga, I. Gabilondo, D. Ganten, A. Gidon, J.C. Gomez-Esteban, P. Greengard, V. Grinevich, A. Gruart, R. Guillemin, A.R. Hariri, B. Hassan, M. Häusser, Y. Hayashi, N.K. Hussain, A.A. Jabbar, M. Jaber, R. Jahn, E.M. Janahi, M. Kabbaj, H. Kettenmann, M. Kindt, S. Knafo, G. Köhr, S. Komai, H. Krugers, B. Kuhn, N.L. Ghazal, M.E. Larkum, M. London, B. Lutz, C. Matute, L. Martinez-Millan, M. Maroun, J. McGaugh, A.A. Moustafa, A. Nasim, K.A. Nave, E. Neher, K. Nikolich, T. Outeiro, L.M. Palmer, O. Penagarikano, I. Perez-Otano, D.W. Pfaff, B. Poucet, A.U. Rahman, P. Ramos-Cabrer, A. Rashidy-Pour, R.J. Roberts, S. Rodrigues, J.R. Sanes, A.T. Schaefer, M. Segal, I. Segev, S. Shafqat, N.A. Siddiqui, H. Soreq, E. Soriano-García, R. Spanagel, R. Sprengel, G. Stuart, T.C. Südhof, J. Tønnesen, M. Treviño, B.M. Uthman, J.C. Venter, A. Verkhratsky, C. Weiss, T.N. Wiesel, E. Yaksi, O. Yizhar, L.J. Young, P. Young, N.H. Zawia, J.L. Zugaza and M.T. Hasan

Neuron 96, 730-735 doi: 10.1016/j.neuron.2017.09.028 (2017)

Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species

Sancho-Vaello, E.; Francois, Patrice; Bonetti, EJ, Lilie, H] ; Finger, S ; Gil-Ortiz, F ; Gil-Carton, D; Zeth, K

Sci Rep.: 7 , 15371 (2017)

Identification and in vitro characterization of two new PCSK9 Gain of Function variants found in patients with Familial Hypercholesterolemia

M.D. Di Taranto, A. Benito-Vicente, C. Giacobbe, K.B. Uribe, P. Rubba, A. Etxebarria, O. Guardamagna, M. Gentile, C. Martin and G. Fortunato

Sci Rep 7, 15282 doi: 10.1038/s41598-017-15543-x (2017)

Editorial on the Special Issue: Molecules and Cognition

A. Barco, S. Knafo

Neuroscience 370, 1-3. Doi10.1016/j.neuroscience2017.11.003. (2017)

Purification and characterization of the colicin A immunity protein in detergent micelles

A. Metola, A.M. Bouchet, M. Alonso-Marino, T. Diercks, L. Maler, F.M. Goni and A.R. Viguera

Biochim Biophys Acta 1859, 2181-2192 doi: 10.1016/j.bbamem.2017.08.007 (2017)

Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria

E. Sancho-Vaello, D. Albesa-Jove, A. Rodrigo-Unzueta and M.E. Guerin

Biochim Biophys Acta 1862,1355-1367 doi: 10.1016/j.bbalip.2016.11.002 (2017)

Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

M.A. Urbaneja, L. Skjaerven, O. Aubi, J. Underhaug, D.J. Lopez, I. Arregi, M. Alonso-Marino, A. Cuevas, J.A. Rodriguez, A. Martinez and S. Banuelos

Sci Rep 7, 13959 doi: 10.1038/s41598-017-14497-4 (2017)

Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels

A. Alaimo, E. Nunez, P. Aivar, J. Fernandez-Orth, C. Gomis-Perez, G. Bernardo-Seisdedos, C. Malo and A. Villarroel

Sci Rep 7, 13425 doi: 10.1038/s41598-017-13811-4 (2017)

Structure-Related Roles for the Conservation of the HIV-1 Fusion Peptide Sequence Revealed by Nuclear Magnetic Resonance

S. Serrano, N. Huarte, E. Rujas, D. Andreu, J.L. Nieva and M.A. Jimenez

Biochemistry 56, 5503-5511 doi: 10.1021/acs.biochem.7b00745 (2017)

Biofilm-Forming Clinical Staphylococcus Isolates Harbor Horizontal Transfer and Antibiotic Resistance Genes

S. Aguila-Arcos, I. Alvarez-Rodriguez, O. Garaiyurrebaso, C. Garbisu, E. Grohmann and I. Alkorta

Front Microbiol 8, 2018 doi: 10.3389/fmicb.2017.02018 (2017)

Environmental parameters altered by climate change affect the activity of soil microorganisms involved in bioremediation

Alkorta, Itziar; Epelde, Lur; Garbisu, Carlos

FEMS Microbiology Letters 364 , fnx200 (2017)

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

J. Miles, C.J. Applebee, P. Leboucher, S. Lopez-Fernandez, D.J. Lee, R. Guarch, S. Ward, P.J. Parker, J.I. Lopez and B.Larijani

BBA Clin 8, 97-102 doi: 10.1016/j.bbacli.2017.10.002 (2017)

Peptides Acting as Cognitive Enhancers

D. Asua, G. Bougamra, M. Calleja-Felipe, M. Morales, S. Knafo

Neuroscience 370, 81-87. Doi: 10.1016/j.neuroscience 2017.10.002 (2017)

Plasmid-Mediated Bioaugmentation for the Bioremediation of Contaminated Soils

Carlos Garbisu, Olatz Garaiyurrebaso, Lur Epelde, Elisabeth Grohmann and Itziar Alkorta

Front Microbiol. 2017; 8: 1966. (2017)

Last issue of journal of chemical biology

R. Woscholski and B. Larijani

J Chem Biol 10, 157 doi: 10.1007/s12154-017-0176-x (2017)

Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes

H. Ostolaza, C. Martin, D. Gonzalez-Bullon, K.B. Uribe and A. Etxaniz

Toxins 9, 295 doi: 10.3390/toxins9100295 (2017)

Effects of HIV-1 gp41-Derived Virucidal Peptides on Virus-like Lipid Membranes

P. Carravilla, A. Cruz, I. Martin-Ugarte, I.R. Oar-Arteta, J. Torralba, B. Apellaniz, J. Perez-Gil, J. Requejo-Isidro, N. Huarte and J.L. Nieva

Biophys J 113, 1301-1310 doi: 10.1016/j.bpj.2017.06.061 (2017)

Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state

J. Chojnacki, D. Waithe, P. Carravilla, N. Huarte, S. Galiani, J. Enderlein and C. Eggeling

Nat Commun 8, 545 doi: 10.1038/s41467-017-00515-6 (2017)

Coating Graphene Oxide with Lipid Bilayers Greatly Decreases Its Hemolytic Properties

B.G, Monasterio, B. Alonso, J. Sot, A.B. Garcia-Arribas, D. Gil-Carton, M. Valle, A. Zurutuza and F.M. Goni

Langmuir 33, 8181-8191 doi: 10.1021/acs.langmuir.7b0155 (2017)

Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain

D. Gonzalez-Bullon, K.B. Uribe, C. Martin and H. Ostolaza

Proc Natl Acad Sci U S A 114, E6784-E6793 doi: 10.1073/pnas.1701783114 (2017)

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

L.A. Rosado, K. Wahni, G. Degiacomi, B. Pedre, D. Young, A.G. de la Rubia, F. Boldrin, E. Martens, L. Marcos-Pascual, E. Sancho-Vaello, D. Albesa-Jove, R. Provvedi, C. Martin, V. Makarov, W. Versees, G. Verniest, M.E. Guerin, L.M. Mateos, R. Manganelli and J. Messens

J Biol Chem 292, 13097-13110 doi: 10.1074/jbc.M117.797837 (2017)

Uncoupling TORC2 from AGC kinases inhibits tumour growth

A.J.M. Cameron, S. Veeriah, J.J.T. Marshall, E.R. Murray, B. Larijani and P.J. Parker

Oncotarget 8, 84685-84696 doi: 10.18632/oncotarget.20086 (2017)

Apoptotic foci at mitochondria: in and around Bax pores

B. Ugarte-Uribe and A.J. Garcia-Saez

Philos Trans R Soc Lond B Biol Sci 372, (1726) pii: 20160217 doi: 10.1098/rstb.2016.0217 (2017)

Analysis of LDLR variants from homozygous FH patients carrying multiple mutations in the LDLR gene

L. Jiang, A. Benito-Vicente, L. Tang, A. Etxebarria, W. Cui, K.B. Uribe, X.D. Pan, H. Ostolaza, S.W. Yang, Y.J. Zhou, C. Martin and L.Y. Wang

Atherosclerosis 263, 163-170 doi: 10.1016/j.atherosclerosis.2017.06.014 (2017)

Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo

C.J. Peddie, M.C. Domart, X. Snetkov, P. O\'Toole, B. Larijani, M. Way, S. Cox and L.M. Collinson

J Estruct Biol 199, 120-131 doi: 10.1016/j.jsb.2017.05.013 (2017)

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function

K. Betteridge, K. Arkill, C. Neal, S. Harper, B. Foster, S. Satchell, D. Bates and A. Salmon

J Physiol. doi: 10.1113/JP274167 (2017)

A High Resolution Study of Dynamic Changes of Ce2O3 and CeO2 Nanoparticles in Complex Environmental Media

Merrifield, RC ; Arkill, KP ; Palme, RE; Lead, JR

Environmental Science & Technology 51 , 8010-8016 DOI: 10.1021/acs.est.7b01130 (2017)

Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research

B. Shirt-Ediss, S. Murillo-Sanchez and K. Ruiz-Mirazo. Beilstein J

Org Chem 13, 1388-1395 doi: 10.3762/bjoc.13.135 (2017)

Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

D. Albesa-Jove, J. Romero-Garcia, E. Sancho-Vaello, F.X. Contreras, A. Rodrigo-Unzueta, N. Comino, A. Carreras-Gonzalez, P. Arrasate, S. Urresti, X. Biarnes, A. Planas and M.E. Guerin

Structure 25, 1034-1044.e3. doi: 10.1016/j.str.2017.05.009 (2017)

Polyamine-RNA-membrane interactions: From the past to the future in biology

C. Acosta-Andrade, I. Artetxe, M.G. Lete, B.G. Monasterio, K. Ruiz-Mirazo, F.M. Goni and F. Sanchez-Jimenez

Colloids Surf B Biointerfaces 155, 173-181 doi: 10.1016/j.colsurfb.2017.04.005 (2017)

Permeability-driven selection in a semi-empirical protocell model: the roots of prebiotic systems evolution

G. Piedrafita, P.A. Monnard, F. Mavelli and K. Ruiz-Mirazo

Sci Rep 7, 3141 doi: 10.1038/s41598-017-02799-6 (2017)

2D IR Correlation Spectroscopy in the Determination of Aggregation and Stability of KH Domain GXXG Loop Peptide in the Presence and Absence of Trifluoroacetate

A.R. Nassif, I. de la Arada, J.L. Arrondo and B. Pastrana-Rios

Anal Chem 89, 5766-5776 doi: 10.1021/acs.analchem.6b04800 (2017)

Complex Effects of 24:1 Sphingolipids in Membranes Containing Dioleoylphosphatidylcholine and Cholesterol

A.B. Garcia-Arribas, E.J. Gonzalez-Ramirez, J. Sot, I. Areso, A. Alonso and F.M. Goni

Langmuir 33, 5545-5554 doi: 10.1021/acs.langmuir.7b00162 (2017)

Label-Free, Multiplexed, Single-Molecule Analysis of Protein-DNA Complexes with Nanopores

G. Celaya, J. Perales-Calvo, A. Muga, F. Moro and D. Rodriguez-Larrea

ACS Nano 11, 5815-5825 doi: 10.1021/acsnano.7b01434 (2017)

High conductance values in π-folded molecular junctions

M. Carini, M. P. Ruiz, I. Usabiaga, J. A. Fernández, E. J. Cocinero, M. Melle-Franco, I. Diez-Perez and A. Mateo-Alonso

Nature Communications volume 8, Article number: 15195 (2017)

The conformation of human phospholipid scramblase 1, as studied by infrared spectroscopy. Effects of calcium and detergent

N. Andraka, L. Sanchez-Magraner, M. Garcia-Pacios, F.M. Goni and J.L.R. Arrondo

Biochim Biophys Acta 1859, 1019-1028 doi: 10.1016/j.bbamem.2017.02.015 (2017)

Differential Regulation of PI(4,5)P-2 Sensitivity of Kv7.2 and Kv7.3 Channels by calmodulin

C. Gomis-Perez, M.V. Soldovieri, C. Maio, P. Ambrosino, M. Taglialatela, P. Areso and A.Villarroel

Front Mol Neurosci 10, 117 doi: 10.3389/fnmol.2017.0011 (2017)

Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems

K. Ruiz-Mirazo, C. Briones and A. de la Escosura

Open Biol 7, 170050 doi: 10.1098/rsob.170050 (2017)

Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane

E. Rujas, S. Insausti, M. Garcia-Porras, R. Sanchez-Eugenia, K. Tsumoto, J.L. Nieva and JJ.M.M. Caaveiro

. J Mol Biol 429, 1213-1226 doi: 10.1016/j.jmb.2017.03.008 (2017)

Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases

N. Comino, J.O. Cifuente, A. Marina, A. Orrantia, A. Eguskiza and M.E. Guerin

J Biol Chem 292, 6255-6268 doi: 10.1074/jbc.M116.773408 (2017)

ICTV Virus Taxonomy Profile: Iflaviridae

S.M. Valles, Y. Chen, A.E. Firth, D.M.A. Guerin, Y. Hashimoto, S. Herrero, J.R. de Miranda and E. Ryabov

J Gen Virol 98, 527-528 doi: 10.1099/jgv.0.000757 (2017)

Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody

E. Rujas, J.M.M. Caaveiro, S. Insausti, M. Garcia-Porras, K. Tsumoto and J.L. Nieva

J Biol Chem 292, 5571-5583 doi: 10.1074/jbc.M117.775429 (2017)

Long-term effects of aided phytostabilisation on microbial communities of metal-contaminated mine soil

O. Garaiyurrebaso, C. Garbisu, F. Blanco, A. Lanzén, I. Martín, L. Epelde, J.M. Becerril, S. Jechalke, K. Smalla, E. Grohmann and I. Alkorta

FEMS Microbiol Ecol. 93, pii: fiw252. doi: 10.1093/femsec/fiw252. (2017)

Membrane-assisted viral DNA ejection

I. Santos-Perez, H.M. Oksanen, D.H. Bamford, F.M. Goni, D. Reguera and N.G.A. Abrescia

Biochim Biophys Acta 1861, 664-672 doi: 10.1016/j.bbagen.2016.12.013 (2017)

Lipidomic profile of GM95 cell death induced by Clostridium perfringens alpha-toxin

M.M. Manni, J.G. Valero, M. Perez-Cormenzana, A. Cano, C. Alonso and F.M. Goni

Chem phys Lipids 203, 54-70 doi: 10.1016/j.chemphyslip.2017.01.002 (2017)

ICTV Virus Taxonomy Profile: Dicistroviridae

S.M. Valles, Y. Chen, A.E. Firth, D.M.A. Guerin, Y. Hashimoto, S. Herrero, J.R. de Miranda and E. Ryabov

J Gen Virol 98, 355-356 doi: 10.1099/jgv.0.000756 (2017)

Novel fluorinated ligands for gold nanoparticle labelling with applications in 19F-MRI

O. Michelena, D. Padro, C. Carrillo-Carrión, P. del Pino, J. Blanco, B. Arnaiz, W. J. Parak, M. Carril

Chemical Communications, 2017, 53, 2447 - 2450. DOI: 10.1039/C6CC08900C (2017)

Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes

I.M. De la Fuente, I. Malaina, A. Perez-Samartin, M.D. Boyano, G. Perez-Yarza, C. Bringas, A. Villarroel, M. Fedetz, R. Arellano, J.M. Cortes and L. Martinez

Sci Rep 7, 41791 doi: 10.1038/srep41791 (2017)

PTEN: Local and Global Modulation of Neuronal Function in Health and Disease

S. Knafo and J.A. Esteban

Trends Neurosci 40, 83-91 doi: 10.1016/j.tins.2016.11.008 (2017)

eC-CLEM: flexible multidimensional registration software for correlative microscopies

P. Paul-Gilloteaux, X. Heiligenstein, M. Belle, M.C. Domart, B. Larijani, L. Collinson, G. Raposo and J. Salamero

Nat Methods 14, 102-103 doi: 10.1038/nmeth.4170 (2017)

Vesicular PtdIns(3,4,5) P-3 and Rab7 are key effectors of sea urchin zygote nuclear membrane fusión

M.G. Lete, R.D. Byrne, A. Alonso, D. Poccia and B. Larijani

J Cell Sci 130, 444-452 doi: 10.1242/jcs.193771 (2017)

Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif

L.M. Molinos-Albert, E. Bilbao, L. Agullo, S. Marfil, E. Garcia, M.L.R. de la Concepcion, N. Izquierdo-Useros, C. Vilaplana, J.A. Nieto-Garai, F.X. Contreras, M. Floor, P.J. Cardona, J. Martinez-Picado, B. Clotet, J. Villa-Freixa, M. Lorizate, J. Carrillo and J. Blanco

Sci Rep 7, 40800 doi: 10.1038/srep40800 (2017)

A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies

R. Subiros-Funosas, L. Mendive-Tapia, J. Sot, J.D. Pound, N. Barth, Y. Varela, F.M. Goni, M. Paterson, C.D. Gregory, F. Albericio, I. Dransfield, R. Lavilla and M. Vendrell

Chem Commun 53, 945-948 doi: 10.1039/c6cc07879f (2017)

Selected Standard Protocols for the Synthesis, Phase Transfer, and Characterization of Inorganic Colloidal Nanoparticles

J. Hühn, C. Carrillo-Carrion, M. G. Soliman, C. Pfeiffer, D. Valdeperez, A. Masood, I. Chakraborty, L. Zhu, M. Gallego, Z. Yue, M. Carril, N. Feliu, A. Escudero, A. Alkilany, B. Pelaz, P. del Pino, W. J. Parak

Chemistry of Materials, 2017, 29, 399 - 461. DOI: 10.1021/acs.chemmater.6b04738 (2017)

Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms

B. Ugarte-Uribe, S. Grijalvo, S.N. Pertinez, J.V. Busto, C. Martin, A. Alagia, F.M. Goni, R. Eritja and I. Alkorta

Bioorg Med Chem 25, 175-186 doi: 10.1016/j.bmc.2016.10.024 (2017)