Publications
2013
Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria.
J Biol Chem. 288, 29797-29808 (2013).
Charge pair interactions in transmembrane helices and turn propensity of the connecting sequence promote helical hairpin insertion.
J Mol Biol. 425, 830-840 (2013).
The transmembrane domain of the T4SS coupling protein TrwB and its role in protein-protein interactions.
Biochim Biophys Acta, 1828, 2015-2025 (2013).
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: first evidence for an altered channel regulation by syntaxin-1A.
Hum Mutat. 35, 356-367 (2013).
Reliable prediction of complex phenotypes from a modular design in free energy space: an extensive exploration of the lac operon.
ACS Synth Biol. 2, 576-586 (2013).
Optical super-resolution: biochemistry in the cell at macromolecular scale.
J Chemical Biology 6(3), 97-120 (2013).
Cross-protomer interaction with the photoactive site in oligomeric proteorhodopsin complexes.
Acta Cryst. D69, 1965–1980 (2013).
The onset of Triton X-100 solubilization of sphingomyelin/ceramide bilayers: effects of temperature and composition.
Chem. Phys. Lipids. 167-168, 57-61 (2013).
Screening and evaluation of small organic molecules as ClpB inhibitors and potential antimicrobials.
J. Med. Chem. 56, 7177-7189 (2013).
A biophysicist in the kitchen.
Flavour, 2:7 (2013).
Probing the biophysical interplay between a viral genome and its capsid.
Nat Chem. 5, 502-509 (2013).
Hofmeister ions control protein dynamics.
Biochim. Biophys. Acta. 1830, 4564-4572 (2013).
Free Fructose is conformationally locked
J. Am. Chem. Soc., 135, 2845-1852 (2013)
A computational module assembled from different protease family motifs identifies PI PLC from Bacillus cereus as a putative prolyl peptidase with a serine protease scaffold.
PLoS One, 8(8):e70923. doi: 10.1371/journal.pone.0070923 (2013).
Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus.
PLoS Pathog. 9:e1003108. doi: 10.1371/journal.ppat.1003108 (2013).
Effects of chronic and acute lead treatments on the biophysical properties of erythro- cyte membranes, and a comparison with model membranes.
FEBS Open Bio 3, 212–217 (2013).
Definir vida: un ejercicio constructivo.
SEBBM 175, 3-6 (2013).
Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells.
Biochim. Biophys. Acta General Subjects 1830: 4872-4884 (2013).
Fourier-space TEM reconstructions with symmetry adapted functions for all rotational point groups.
J. Struct. Biol. 182, 87-92 (2013).
Calpain-mediated processing of adenylate cyclase toxin generates a cytosolic soluble catalytically active NTerminal domain.
PLoS One 8, Issue 6 | e67648 (2013).
Cooperativity between calmodulin-binding sites in Kv7.2 channels.
J. Cell Sci. 126, 244-253 (2013).
Structural insights into the chaperone activity of the 40-kDa heat shock protein DnaJ: binding and remodeling of a native substrate.
J. Biol. Chem. 288, 15065-15074 (2013).
The use of dansyl-calmodulin to study interactions with channels and other proteins.
Methods Mol. Biol. 998, 217-231 (2013).
Membrane partitioning of the pore-forming domain of Colicin A. role of the hydrophobic helical hairpin.
Biophys. J. 105, 1432-1443 (2013).
The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the m-current.
J Neurosci. 33, 2684-2696 (2013).
2012
Viroporins: structure and biological functions.
Nat Rev Microbiol. 10, 563-74 (2012).
Model systems of precursor cellular membranes: long-chain alcohols stabilize spontaneously formed oleic acid vesicles.
Biophys. J. 102, 278–286 (2012).
Recognition of membrane-bound fusion-peptide/MPER complexes by the HIV-1 neutralizing 2F5 antibody: implications for Anti-2F5 immunogenicity.
PLoS One, 7, e52740. doi: 10.1371 (2012).
Phospholipases C and sphingomyelinases: Lipids as substrates and modulators of enzyme activity.
Prog Lipid Res 51, 238–266 (2012).
A global survey of CRM1-dependent nuclear export sequences in the human deubiquitinase family.
Biochem. J. 441, 209–217 (2012).
Insights into sphingolipid miscibility: separate observation of sphingomyelin and ceramide N-acyl chain melting.
Biophys J. 103, 2465-2474 (2012).
Viability conditions for a compartmentalized proto-metabolic system: a semi-empirical approach
PLoS ONE 7(6): e39480 (2012)
Functional characterization of splicing and ligand-binding domain variants in the LDL receptor.
Hum Mutat. 33, 232-43 (2012).
Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides.
PLoS Biol. 10(12):e1001448. doi: 10.1371/journal.pbio.1001448 (2012).
Common pathways for growth and for plasticity.
Curr Opin Neurobiol 22, 405-411, doi:10.1016/j.conb.2012.02.008 (2012)
Deletion of a single helix from the transmembrane domain causes large changes in membrane insertion properties and secondary structure of the bacterial conjugation protein TrwB
Biochim Biophys Acta. 1818, 3158-3166 (2012).
Microscale AMPAR reorganization and dynamics of the postsynaptic density.
J. Neurosci 32, 7103-7105, doi:10.1523/ JNEUROSCI.1048-12.2012 (2012).
Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes.
J. Struct. Biol. 180, 312-317 (2012).
Accumulated bending energy elicits neutral sphingomyelinase activity in human red blood cells.
Biophys. J. 102 2077–2085 (2012).
A new view of the lethal apoptotic pore.
PLoS Biology, 10, (9) e1001399 (2012).