Miguel García Porras
Laboratory technician
Publications
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BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL
H Flores-Romero, O Landeta , B Ugarte-Uribe, K Cosentino, M García-Porras, AJ García-Sáez, G Basañez.
Cell Death Differ. doi: 10.1038/s41418-018-0258-5. (2019)
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Membrane insertion of the BAX core, but not latch domain, drives apoptotic pore formation
H. Flores-Romero, M. Garcia-Porras and G. Basanez
Sci Rep 7, 16259 doi: 10.1038/s41598-017-16384-4 (2017)
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Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane
E. Rujas, S. Insausti, M. Garcia-Porras, R. Sanchez-Eugenia, K. Tsumoto, J.L. Nieva and JJ.M.M. Caaveiro
. J Mol Biol 429, 1213-1226 doi: 10.1016/j.jmb.2017.03.008 (2017)
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Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody
E. Rujas, J.M.M. Caaveiro, S. Insausti, M. Garcia-Porras, K. Tsumoto and J.L. Nieva
J Biol Chem 292, 5571-5583 doi: 10.1074/jbc.M117.775429 (2017)
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Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface
E. Rujas, J.M. Caaveiro, A. Partida-Hanon, N. Gulzar, K. Morante, B. Apellániz, M. García-Porras, M. Bruix, K. Tsumoto, J.K. Scott, M.A. Jiménez and J.L. Nieva.
Sci Rep. 6, 38177 doi.10.1038/srep38177 (2016)
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Lipid-dependent bimodal MCL1 membrane activity.
O. Landeta, J.G. Valero, H. Flores-Romero, I. Bustillo-Zabalbeitia, A. Landajuela, M. García-Porras, O. Terrones and G. Basañez.
ACS Chem Biol. 9, 2852-2863 (2014).