Systems Biophysics and Computational Biology

Systems Biophysics and Computational Biology

Our research activity is focused on computational and mathematical analysis of biological systems at their various levels of organization, from molecular properties to cell behaviour and the role these play in the cell population dynamics. The main objective is to deepen our understanding of the underlying mechanisms and to use this information for the controlling and designing cellular processes. For this, we use the latest computational technologies with a wide range of methods including molecular dynamics, structural bioinformatics, stochastic simulation algorithms and mathematical analysis of dynamic systems. Using these computational biophysical techniques, together with corresponding experimental results, we are studying proteins, nucleic acids and lipids, as well as their interactions, their collective properties and the dynamics of their macromolecular complexes in networks of gene expression and signal transduction.

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