Fluorinated nanostructures as tools for imaging and delivery (FluoroNanoTools)

Fluorinated nanostructures as tools for imaging and delivery (FluoroNanoTools)

The research of the group is mainly focused on the use of fluorinated nanostructures as enabling tools to learn about dynamic biological processes. On the one hand, we use fluorine as a label that can be tuned for the design of OFF/ON or Smart contrast agents based on 19F MRI or as a reporter for the study of protein corona in complex environments via fluorine based magnetic resonance (19F NMR, MRS or MRI). On the other hand, we take advantage of the particular properties of organic fluorine for encapsulation and delivery purposes inside cells. In this field, we aim at tuning the nanoparticles’ surface to achieve controlled interaction with cell membranes to direct and improve delivery.

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